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Template-based RNA tertiary structure prediction
 Galvánek, Rastislav ; Hoksza, David (advisor) ; Jelínek, Jan (referee)
The thesis deals with proposal, implementation and testing of a new algorithm for homologous tertiary RNA structure prediction, which means using a structure similar to the template. It focuses on the possibility of large RNA structures prediction in reasonable time and precision. The algorithm is based on copying conserved parts of template structure into the target structure. The unconserved parts are then predicted by an existing ab initio algorithm. The thesis is divided into four chapters. The first one contains basic information about RNA and its importance. The second one describes different ways of RNA prediction and it contains an overwiev of currently available prediction methods. The third one describes the invented algorithm and the fourth one presents achieved results.
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