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Circadian system of the retina
Kozel, Tomáš ; Bendová, Zdeňka (advisor) ; Moravcová, Simona (referee)
Most of the known living organisms have developed an evolutionary adaptation to a 24-hour daily rhythm. This rhythm, known as circadian rhythm, can be preserved even in the environment, in which there is no access to light or other synchronizer. The master organ of circadian rhythm is located in the hypothalamic suprachiasmatic nucleus (SCN) and have been considered the only autonomous circadian oscillator for a long time. The new research, however, has doubted this hypothesis by showing the existence of autonomous circadian clock systems independent of SCN. One of these autonomous clocks is the circadian system in the retina. This bachelor thesis reviews current scientific knowledge on the function of mammalian retinal circadian oscillator, most importantly in the field of its localization, connection with the SCN master circadian oscillator and its influence on retinal physiology.

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