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Prognostic indicators of risk of death and the consequences of purulent meningitis
 Džupová, Olga ; Janovská, Daniela (advisor) ; Křížová, Pavla (referee) ; Marešová, Vilma (referee) ; Dostál, Václav (referee)
Purulent meningitis is a life-threatening acute infectious disease of the central nervous system. In preantibiotics period was almost one hundred percent fatality rate of disease, with the discovery of antibiotics and their introduction into medical practice in 30th-50th of the last century has decreased dramatically. In recent decades, despite the use of highly effective antibiotics and intensive care procedures, there was no significant reduction in mortality rate and consequences of the disease. Lethal course of the disease affects 15-30% of patients in adulthood. Although not a common infection diagnosis among the top ten infectious causes of death worldwide. The study was based on evaluation of their own group of patients to determine prognostic factors observed history, course of illness and laboratory characteristics of the clinical outcome of disease in adults.
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