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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Serotonergic hallucinogenes and their therapeutic use
 Bouberl, David ; Novotný, Jiří (advisor) ; Vejmola, Čestmír (referee)
Serotonergic hallucinogens are a group of substances that induce changes in consciousness based on their affinity for some of the serotonin receptors - especially 5-HT2A. The best known substances in this group include LSD, psilocybin or mescaline. During the 1950's and 1960's, initial research into the therapeutic uses of these substances took place, but studies from this period did not meet today's methodological standards. However, the results of recent studies point to the potential therapeutic use of psilocybin or LSD in the treatment of depression / anxiety, addiction and OCD. The aim of this work is to summarize current knowledge about selected serotonergic hallucinogens, their chemical properties, mechanisms of action and especially about the possibilities of using these substances in psychotherapy.
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Biologická charakteristika dendritických buněk
 Coufalová, Karmela
This thesis deals about characteristics of dendritic cells. Dendritic cells are antigen presenting cells that can stimulate naive T and B cells and they can regulate immune response of organism. They differ from other cells in that they can express MHC I and MHC II molecules and in that they do not have surface immunoglobulines or lymphocytic and monocytic characters. Dendritic cells are spread nearly through all tissues of the organism. There are two main pathways myeloid and lymphoid. Dendritic cells have two forms: immature (tolerogenic) and matture (immunoregulatory). Follicular dendritic cells are special case of dendritic cells. They are morphologically similar to dendritic cells, but they have not the same origin. Dendritic cells can represent vector for immunotherapy of allergic diseases, infections, autoimmune diseases, tumor immunotherapy and they can play role also in transplantology. Recently, research deals with antitumor vaccination.
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