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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Complete differential diagnostics of monoklonal gammopathy
 MERVARTOVÁ, Ivana
The aim of the thesisis a quantitative detection of the monoclonal paraprotein in patients serum, eventually a qualitative detection in urine in group of hematological pacients examined at the Department of clinical biochemistry in Hospital Písek a.s. with electrophoretic analytical method (ELFO) and its subsequent specification by immunofixation electrophoresis (IFE). The quantification of free light chains (VLR), kappa and lambda, from the serum is made on some patients for more complex information, and it is made by immunoanalytic method. Futhermore immunoglobulins as well as values of albumin and values of total protein are quantitatively established in the serum, and these values can contribute to more precise diagnosis in case of finding of monoclonal components. From the stated hypothesis I conclude, that the patients with pathological values VLR and their ratios, which lead to diagnosis of the monoclonal gammopathy, will also have positive finding of monoclonal immunoglobulin on ELFO. The finding will be afterwards specified by IFE method and so the diagnosis of monoclonal gammopathy will be confirmed.
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