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Schistosoma mansoni (Trematoda): Differences in the biology of geographical strains
Žirovnická, Tereza ; Macháček, Tomáš (advisor) ; Peterková, Kristýna (referee)
This bachelor thesis discusses the geographical strains of the fluke Schistosoma mansoni and summarizes the knowledge of their differences. The thesis aims to conduct literature research of comparative studies mentioning descriptions of specific strains of S. mansoni and then to identify differences across those geographic strains. Among the relevant data subjected to comparisons, besides morphological and anatomical differences, the prepatent period, the distribution of eggs in the host and the caused pathology, including the granuloma formation, were mentioned too. The results of this work confirm that the specific geographical isolates differ from each other in various aspects, often even within the same strain. Geographic strains are unevenly represented in studies, and this may bias our view of selected aspects of schistosome biology through the results of dominant strains. It is therefore important to encourage further, diversified research that considers all experimental factors. The obtained knowledge about the characteristics of geographic strains can provide important information for the development of strategies to control schistosomiasis and benefit negatively affected populations worldwide. Keywords: Schistosoma mansoni, schistosomiasis, geographical strain, comparative analysis,...
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