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Inheritance of coat color in horses
Krejčová, Lucie ; Sedláková, Vladimíra (advisor) ; Hofmanová, Barbora (referee)
Genetic side of horse´s coloring is an interesting topic, which has been a subject of many researches for a long time. The DNA testing has shown that the original horses were brown or buckskin and due to changes in environmental conditions also black. During the domestication circulating more colors, quickly began, helped by human selection. The color of the coat is a quality feature and is subjected to Mendel's rules, for each color of the horses are therefore responsible genes of large effect. To most of the color is already assigned to a specific gene mutation and it is identified that the gene can find and change the phenotype. An exception is the color white, roan and tobiano, known only, that are associated with the KIT gene, dun color and leopard are currently only assigned to chromosomes ECA8 and ECA1. Mutations on genes are of different character, in the MC1R gene, MATP, PMEL17 and SLC36A1 is a change of a single base pair in a gene EDNRB is a dinucleotide mutation. ASIP gene mutation is caused by deletion of 11 nucleotide pairs and on the other hand is caused by mutations STX17 duplication 4.6 kilobytes Knowledge of gene structure and mutations is necessary for testing the color of horses at the molecular level. DNA testing is still in development, but currently it is already possible to test horses to most of the colors, which is important in the accurate identification of colors, but also in preventing the development of diseases which are associated with some genotypes. The aim of this work is to organize and unify information on various horse´s colours and the manner of their inheritance, due to the increasing interest of the people and farmers on this issue.
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