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Study of chemical communication in the house mouse: a proteomic approach
Janotová, Kateřina ; Stopka, Pavel (advisor) ; Piálek, Jaroslav (referee) ; Vošlajerová, Barbora (referee)
Chemical communication of the house mouse is similarly as in other mammals, substantially complex and influence every social ineraction between individuals. Important part of mouse chemical signalling system is Major Urinary Protein complex (MUP). These proteins are known as pheromone-carriers that prolong longevity of the pheromones by retarding their evaporation from the scent mark. Their other role in chemical communication is direct signalling which is mediated by VNO. MUP have been shown to trigger both behavioural and physiological effects in recipient. Proteins belonging to the same family (lipocalins) as MUPs, have been found in other, mainly rodent, species. Although the information about these urinary lipocalins are, with exception of mouse, very limited, it is likely that their roles relies in chemical communication. The Ph.D. thesis is related to the urinary proteins in the house mouse and Mastomys coucha. Thesis contains four chapters represented by three published and one submitted manuscript. One aim of the thesis is to provide information about these proteins in the subspecies Mus musculus musculus which is widespread in the Czech Republic and which is much less studied when compared to Mus musculus domesticus. The part of Ph.D thesis is a review publication which summarizes recent...
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