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Modelování růstu kostní chrupavky na biodegrabilním scafoldu při mechanickém zatěžování.
Kozák, Jakub ; Stará, Jana (referee) ; Maršík, František (advisor)
In the present work we study modeling of hyaline cartilage growth. We start with exploration of the background of the problem, i.e. biology of cartilage, possibilities of cartilage healing and methods of tissue engineering. Derivation of modified mass action law follows. It provides possibility of including chemical reactions and mechanical stimuli into the model. We use this equation for mathematical formulation of the cartilage growth model, which has the form of reaction-diffusion equations. This model is analyzed then and compared with the experiment. It gives some parameters of the model which quantitatively describe cartilage growth in vitro.

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