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Perfusion Modelling in Optical Coherence Tomography
Štohanzlová, Petra ; Penhaker,, Marek (referee) ; Kudrna,, Petr (referee) ; Kolář, Radim (advisor)
This thesis deals mainly with perfusion modeling in optical coherence tomography (OCT). The introductory part deals with basic theory of the OCT, including a description of its basic applications. Part of the work was the testing of selected contrasting materials suitable for the OCT and the design and implementation of phantoms, which were subsequently used in the main part of the thesis. In the practical part, attention is paid to the perfusion analysis in the OCT, first the application of the dilution theory in the OCT for flow estimation, then a study testing the basic theory of perfusion on OCT by means of tissue phantom. Another part of the thesis is devoted to the method of speckle variance analysis for flow visualization.
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Perfusion Modelling in Optical Coherence Tomography
Štohanzlová, Petra ; Penhaker,, Marek (referee) ; Kudrna,, Petr (referee) ; Kolář, Radim (advisor)
This thesis deals mainly with perfusion modeling in optical coherence tomography (OCT). The introductory part deals with basic theory of the OCT, including a description of its basic applications. Part of the work was the testing of selected contrasting materials suitable for the OCT and the design and implementation of phantoms, which were subsequently used in the main part of the thesis. In the practical part, attention is paid to the perfusion analysis in the OCT, first the application of the dilution theory in the OCT for flow estimation, then a study testing the basic theory of perfusion on OCT by means of tissue phantom. Another part of the thesis is devoted to the method of speckle variance analysis for flow visualization.
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Biventricular pacing parameters monitoring depending on the configuration of the left-ventricle lead
Procházka, Antonín ; Korpas, David (advisor) ; Penhaker, Marek (referee)
The aim of the study is to monitor three biventricular pacing parameters measured in the left-ventricle: stimulation threshold, impedance and R-wave voltage. The progression of parameters depending on the configuration of the left-ventricle lead is evaluated in this study. First aim of this study is to evaluate if the configuration has an effect on the progression of parameters. Second aim of this study is to detect and evaluate an effect of the used device. The data were collected at three intervals: day of implantation, 2nd - 5th month after implantation and 8th - 15th month after implantation. Repeated measures analysis of variance (ANOVA) and software Matlab and Statistica were used for the statistical analysis. The configuration of the left-ventricle lead and also used device were used as factors in ANOVA. The progression of parameters depending on configuration of the left-ventricle lead is not statistically significant for all quantities. Impedance with LV tip > LV ring configuration is significantly greater in every interval than impedance with other configurations. R-wave voltage and impedance increase significantly between implantation and 2nd interval and between implantation and 3rd interval. Used device does not influence values and time progression of measured parameters...
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