|
|
The evaluation of stress relaxation of lactose and calcium hydrogen phosphate mixtures intended for the preparation of tablets with theophylline.
Le, Thanh Tra ; Svačinová, Petra (advisor) ; Ondrejček, Pavel (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical technology Consultant: Mgr. Petra Svačinová, PhD. Student: Le Thanh Tra Title of Thesis: Evaluation of stress relaxation of mixtures of lactosum and calcii hydrogenphosphate for preparation tablets with theophylline This thesis studies viscoelastic behavior of fillers and tensile strength of tablets with theophylline. Used material are described in theoretical part: Laktosum SpheroLac 100, microcrystalline cellulose Comprecel 102, calcium hydrogenophosphate anhydrate Di-Cafos A150, calcium hydrogenophosphate dihydrate Di-Cafos D160, theophylline and magnesium stearate. Thesis also describes the stress relaxation test, methods of evaluation and it's application. Experimental part evaluates viscoelastic behavior and tensile strength through the test of stress relaxation with maximal compression force 10 kN and dwell time 180 s. The tensile strength of tablets is also evaluated. Experimental part evaluates parameters of elasticity Ai and plasticity Pi, which were obtained from the test of stress relaxation. It evaluates effect of different fillers on these parameters. The highest values were measured at mixtures E (Spherolac 100 a Comprecel 102), further at mixtures D (Spherolac 100 a Di-Cafos A150) and...
|
|
|
Development of trainable policies for spoken dialogue systems
Le, Thanh Cong ; Jurčíček, Filip (advisor) ; Peterek, Nino (referee)
Abstract Development of trainable policies for spoken dialogue systems Thanh Le In humanhuman interaction, speech is the most natural and effective manner of communication. Spoken Dialogue Systems (SDS) have been trying to bring that high level interaction to computer systems, so with SDS, you could talk to machines rather than learn to use mouse and keyboard for performing a task. However, as inaccuracy in speech recognition and inherent ambiguity in spoken language, the dialogue state (user's desire) can never be known with certainty, and therefore, building such a SDS is not trivial. Statistical approaches have been proposed to deal with these uncertainties by maintaining a probability distribution over every possible dialogue state. Based on these distributions, the system learns how to interact with users, somehow to achieve the final goal in the most effective manner. In Reinforcement Learning (RL), the learning process is understood as optimizing a policy of choosing action conditioned on the current belief state. Since the space of dialogue...
|
|
|
The evaluation of stress relaxation of lactose and calcium hydrogen phosphate mixtures intended for the preparation of tablets with theophylline.
Le, Thanh Tra ; Svačinová, Petra (advisor) ; Ondrejček, Pavel (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical technology Consultant: Mgr. Petra Svačinová, PhD. Student: Le Thanh Tra Title of Thesis: Evaluation of stress relaxation of mixtures of lactosum and calcii hydrogenphosphate for preparation tablets with theophylline This thesis studies viscoelastic behavior of fillers and tensile strength of tablets with theophylline. Used material are described in theoretical part: Laktosum SpheroLac 100, microcrystalline cellulose Comprecel 102, calcium hydrogenophosphate anhydrate Di-Cafos A150, calcium hydrogenophosphate dihydrate Di-Cafos D160, theophylline and magnesium stearate. Thesis also describes the stress relaxation test, methods of evaluation and it's application. Experimental part evaluates viscoelastic behavior and tensile strength through the test of stress relaxation with maximal compression force 10 kN and dwell time 180 s. The tensile strength of tablets is also evaluated. Experimental part evaluates parameters of elasticity Ai and plasticity Pi, which were obtained from the test of stress relaxation. It evaluates effect of different fillers on these parameters. The highest values were measured at mixtures E (Spherolac 100 a Comprecel 102), further at mixtures D (Spherolac 100 a Di-Cafos A150) and...
|
|
|
Identification of Shocks and Imbalances in the European Union
Le, Thanh Tam
The main objective of the thesis is to examine the asymmetric shocks and imbal-ances among the countries in the European Union. The shocks are identified with their nature and estimated in magnitudes by using the Vector Autoregressive models. From these models, the filtered residuals representing economic shocks were displayed on correlation matrices in order to assess the similarity level of their impacts on respective member states' economies. The empirical studies led to the conclusion that there exist some certain asymmetries in the EU and enabled some policy implications.
|
|
| |
|
| |
guest ::
