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National Repository of Grey Literature

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Study of clinically applicable cancer immunotherapy and their mechanisms GLASEROVÁ, Simona The aim of this thesis was study of replacement of LPS in innate immunity based cancer immunotherapy. Application of poly (I:C) with mixture of mannan-SMCC + R-848.HCl leads to synergy, higher reduction of tumor growth and significant prolongation of survival. The significance and mechanism of action of neutrophils have also been studied within this therapy. Detailed record

Study of melanoma B16-F10 therapy based on LPS application GLASEROVÁ, Simona The purpose of this study was to evaluate the influence of lipopolysaccharide on tumour growth and metastases formation. We studied toxicity and the effect of different concentrations of lipopolysaccharide on tumour growth and toxicity in both in vitro and in vivo experiments. Detailed record

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