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Nutritional status of patients with colorectal cancer before the diagnosis and during the therapy
Fousková, Diana ; Turková, Hana (advisor) ; Křížová, Jarmila (referee)
This diploma thesis focuses on the nutritional status of patients with colorectal cancer. In the theoretical part I describe the incidence, risk factors of colorectal cancer, clinical manifestations, diagnostics, individual types of anticancer therapies, their side effects and dietary recommendations for individual gastrointestinal side effects of anticancer therapy. In the theoretical part I also focus on malnutrition and nutritional support in the treatment of colorectal cancer. Also important is the prevention of colorectal cancer, which is described in the last section. The aim of the research is to compare the eating habits and lifestyle of patients with colorectal cancer before the diagnosis and during the therapy. The second objective is to compare the weight of the patients before the diagnosis and therapy and to find out the most common causes of weight loss in anticancer therapy. The third objective is to find out whether patients who have had a sipping support during their anticancer therapy will regain their weight compared to patients who did not. The research was conducted through a questionnaire survey. A total of 55 oncology patients with colorectal cancer diagnosis were present. The research was conducted in two hospitals in oncology departments and oncological ambulances. The...
Nutrition of patients in oncology departments
FOUSKOVÁ, Diana
The title of my bachelor thesis is Nutrition of Patients in Oncology Departments. In the theoretical part, I focused on the characteristics of malnutrition cancer, its symptoms, types of tumor malnutrition, its causes and consequences. Then I mentioned and described the various changes in metabolism of an oncology patient and a diagnosis of malnutrition. In the next part I described various types of nutritional support. In the theoretical part, I also focused on cancer therapy, where I described types of cancer treatment, various side effects of cancer therapy associated with intake of food and beverages and for every undesirable side effect I stated dietary recommendations. In the last part I mentioned risk factors and prevention of cancer. The goal of the practical part of my bachelor thesis was to determine the nutritional status of hospitalized patients in oncology departments in the context of anticancer therapy. I responded to three research questions: 1. "How does the antitumor therapy affect quality and quantity of consumed food?" 2. "How often must parenteral and enteral nutrition be applied to these patients?" 3. "How does the antitumor therapy affect the patient's weight?" The method quantitative and qualitative research was used for processing of the research part. The research was conducted by creating a week's records of diet, which were recorded by hospitalized patients in two departments of oncology. The research sample consisted of 50 oncology patients. Week's records of diet were recorded by 30 patients at University Hospital in Olomouc and by 20 patients at the University Hospital in Motol, Prague. The results were processed by Nutriservis software. Values of energy, protein, fat and carbohydrates calculated by Nutriservis software were compared with the recommended values corresponding with weight and age of the patient. I also examined the number of cases of parenteral and enteral nutrition and weight loss during cancer therapy by having records of the patient's weight at the beginning of anticancer treatments and their current weight. All patients were in the second half of anticancer treatment. I learned this information from patient documentation. To be allowed to have a look into the patient's documentation I prepared informed consent form, which I had consequently signed by the patients. The processed data are interpreted using tables and graphs, which are always accompanied by commentary. I have divided patients into groups according to diagnoses for evaluation. The results show that most patients have an inadequate intake of energy and essential nutrients. Food intake of patients has shown to be dependant on the type of tumor. Patients with carcinomas of the upper digestive tract, colon and carcinomas of liver, gall bladder and pancreas have larger deficiency of energy, proteins, fats and carbohydrates in comparison to patients with genital carcinomas. Patients with carcinomas of the kidney and urinary tract have also shown a significant deficit of energy, protein, fat and carbohydrates. The nutritional support was very common, particularly to patients to whom the tumor caused obstruction of some part of their digestive tract. As for carcinomas of the upper digestive tract, PEG is implemented to most patients. Very common was providing of sipping as an addition to their normal diet and in case of major nutrition complications parenteral nutrition was also often applied. The weight loss was apparent on most the patients. How significant was the weight loss depended on the type of tumor. Adequate intake of energy, nutrients and drinks during anticancer treatment is very important for patients. In the case of formation or developement of tumor malnutrition or developement of complications associated with food intake, nutritional support should be ensured timely according to patient's individual condition.

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