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National Repository of Grey Literature

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Gene NQO1 polymorphism analysis using the PCR method ŠKOPKOVÁ, Stanislava This bachelor thesis deals with the detection of polymorphism of the NQO1 gene by PCR-RFLP methods. The thesis describes the exact methodology of detection of polymorphism commonly used in the clinical laboratory. The methodology including DNA isolation, determination of DNA concentration, PCR, RFLP, and electrophoresis. The detection was performed in 120 patients in genetic laboratory GENLABS s.r.o. in České Budějovice. The results of the analysis were evaluated and compared with the literature. Detailed record

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