Original title: Species transport immersed boundary solver for QCM biosensor: initial developments
Authors: Studeník, Ondřej ; Kubíčková, Lucie ; Kočí, P. ; Isoz, Martin
Document type: Papers
Conference/Event: Conference on Topical Problems of Fluid Mechanics, Praha (CZ), 20250217
Year: 2025
Language: eng
Abstract: Detection of life-threatening pathogens in water can be done by Quartz Crystal Microbalance (QCM) biosensors. The pathogenic species get trapped at the crystal surface leading to a measurable change in the crystal resonant frequency. As a microfluidic device, QCM operates under diffusion-limited conditions and in its current design, most of the analyte is trapped in regions with no or limited crystal sensitivity. Our long term goal is to improve the QCM sensor sensitivity through optimization of its geometry. The optimization will leverage the immersed boundary method to mitigate the need of creating a separate mesh for each tested design. The device performance will be evaluated by simulating the analyte transport in the sensor. In this contribution, we present the development and verification of a mass-preserving flux correction at the immersed boundary, which is the basis of the required transient solver for analyte transport in the presence of immersed boundaries.
Keywords: biosensor; CFD; immersed boundary method; OpenFOAM; scalar transport
Project no.: EH23_020/0008501, TN02000069
Funding provider: GA MŠk, GA TA ČR
Host item entry: Topical Problems of Fluid Mechanics 2025, ISBN 978-80-87012-05-5, ISSN 2336-5781
Note: Související webová stránka: https://tpfm.it.cas.cz/im/im/proceeding/2025/30

Institution: Institute of Thermomechanics AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0372366

Permalink: http://www.nusl.cz/ntk/nusl-692688


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