Original title: Analysis of Temporal Speech Impairments in Prodromal Dementia with Lewy Bodies
Authors: Davaajargal, Anar ; Novotny, Krystof
Document type: Papers
Language: eng
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: Dementia with Lewy bodies (DLB) is the second most common form of neurodegenerative dementia. The progressive deterioration of motor and cognitive functions, accompanied by behavioral changes, severely impacts the quality of life of affected individuals and those around them. Early diagnosis is therefore essential for timely intervention and appropriate treatment. Despite its possible clinical significance, research specifically addressing speech impairments in DLB remains limited. Acoustic analysis offers a cost-effective, non-invasive approach for paraclinical diagnosis, yet its potential in identifying DLB-specific speech patterns remains partially underexplored. This study investigates a key aspect of speech production—temporal parameters (related to speech tempo and pauses), with an extension into the linguistic domain. Statistical evaluation was conducted using the Mann-Whitney U test and descriptive analysis. Notable discriminatory power in differentiating the prodromal DLB group from healthy controls was observed for parameters such as MWPM of Longer Words, Median Pause Length, Occurrence of Repeated Words, and Net Speech Rate, particularly in the monologue task, which exhibited greater effectiveness compared to the text-reading task. This analysis underscores the potential utility of temporal speech parameters for the early detection of DLB while also introducing and evaluating novel custom metrics tailored for this purpose.
Keywords: acoustic analysis; dementia with Lewy bodies; digital speech biomarkers; temporal speech parameters
Host item entry: Proceedings II of the 31st Conference STUDENT EEICT 2025: Selected papers, ISBN 978-80-214-6320-2, ISSN 2788-1334

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: https://hdl.handle.net/11012/255321

Permalink: http://www.nusl.cz/ntk/nusl-687809


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Universities and colleges > Public universities > Brno University of Technology
Conference materials > Papers
 Record created 2025-08-03, last modified 2025-08-03


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