Název:
Combining Hollow Fiber Microextraction with Square Wave Voltammetry at Screen-Printed Boron-Doped Diamond Electrodes for the Determination of Trazodone in Urine
Autoři:
Labzova, Oleksandra ; Hrdlička, Vojtěch ; Navrátil, Tomáš ; Šelešovská, R. Typ dokumentu: Příspěvky z konference Konference/Akce: Modern Electrochemical Methods /44./, Jetřichovice (CZ), 20250519
Rok:
2025
Jazyk:
eng
Abstrakt: A new hollow fiber-based liquid-phase microextraction (HF-LPME) method for the determination of antidepressant medication trazodone (TRZ) in biological samples was developed. HF-LPME was\ncombined with optimized square wave voltammetry (SWV) on a screen-printed boron-doped diamond electrode (SP-BDDE). Optimum HF-LPME conditions were: supported liquid membrane\n(SLM) isoamyl benzoate, 0.1 mol L−1 H2 SO4 as acceptor solution, BRB (pH = 10) as donor phase, and time of extraction 35 min. Limits of quantification (LOQ) and detection (LOD) were 42 and\n12 nmol L−1 , respectively. The applicability of the developed method was verified on human urine.
Klíčová slova:
Hollow fiber liquid-phase microextraction; Screen-printed boron-doped diamond electrode; trazodone Číslo projektu: EH22_008/0004558 Poskytovatel projektu: GA MŠk Zdrojový dokument: Proceedings of the International Conference 44th Modern Electrochemical Methods, ISBN 978-80-908947-2-3
Instituce: Ústav fyzikální chemie J. Heyrovského AV ČR
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Informace o dostupnosti dokumentu:
Dokument je dostupný na vyžádání prostřednictvím repozitáře Akademie věd. Původní záznam: https://hdl.handle.net/11104/0366961