Original title: Identification Of Genetic Heterogeneity In Sequencing Data
Authors: Bartoň, Vojtěch
Document type: Papers
Language: cze
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: This paper describes the preparation of data obtained from Illumina sequencing platform to analyze low frequency genetic changes within population of Treponema strains, i.e. DNA heterogeneity. A method of characterization of raw sequencing data is proposed. The method includes data filtering to achieve better quality of the collected data and calculation of parameters determining which ones of the DNA changes should be considered as heterogeneity.
Keywords: genetic heterogeneity; reads quality; sequencing
Host item entry: Proceedings of the 23st Conference STUDENT EEICT 2017, ISBN 978-80-214-5496-5

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/187067

Permalink: http://www.nusl.cz/ntk/nusl-678021


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