Original title:
Counteracting constitutive activity of Orai1 with an H171Y mutation
Authors:
MARKO, Ricarda Document type: Bachelor's theses
Year:
2021
Language:
eng Abstract:
The functions and structures of the Orai1-ANSGA mutation are still not completely known. To further investigate possible changes in pore structure, Orai1 ANSGA and H171Y in combination with different amino acids were used in cysteine-crosslinking studies, to see if the ANSGA and H171Y mutations affect the orientation of pore-lining residues.
Keywords:
ANSGA; Ca2+ channels; cysteine-crosslinking; H171Y; Ion channels; Orai1 Citation: MARKO, Ricarda. Counteracting constitutive activity of Orai1 with an H171Y mutation. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/66111