Název:
Monitoring The Parameters Of Cells Migrating In Pseudo-3d Extracellular Matrix
Autoři:
Zumberg, Inna Typ dokumentu: Příspěvky z konference
Jazyk:
cze
Nakladatel: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstrakt:
Cell migration plays an essential role in a number of biological processes, such as embryogenesis,the immune response, wound healing and inflammation. Most research regarding cellmigration is based on experiments using two-dimensional (2D) cell cultures, and the detailed molecularand biophysical mechanisms of these processes are already well known. However, muchless is known about cell behaviour in the three-dimensional (3D) environment of living tissues.Pseudo-three-dimensional (pseudo-3D) cell cultures bridge the gap between 2D and 3D geometriesand combine their advantages. This review presents the quantitative evaluation of human mesenchymalstem cells (hMSCs) migration parameters in pseudo-3D artificial extracellular matrix(ECM) of various compositions.
Klíčová slova:
Collagen; Confocal microscopy; Extracellular matrix; hMSCs; Pseudo-3D Zdrojový dokument: Proceedings I of the 27st Conference STUDENT EEICT 2021: General papers, ISBN 978-80-214-5942-7
Instituce: Vysoké učení technické v Brně
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Informace o dostupnosti dokumentu:
Plný text je dostupný v Digitální knihovně VUT. Původní záznam: http://hdl.handle.net/11012/200769