Original title: Vývoj, optimalizace a validace analytické metody na stanovení antibiotika ciprofloxacin ve vodě pomocí LC/MS
Authors: VACLOVÁ, Jana
Document type: Bachelor's theses
Year: 2018
Language: cze
Abstract: This bachelor thesis deals with the development, optimization and validation of an analytical method for determination of antibiotic ciprofloxacin in water using LC/MS. At first, the development and optimization of the analytical method was performed. The following parameters were selected for optimization: mobile phase composition and injection volume of sample, conditions of electrospray, voltage on S-lens and F-lens, collision energy, maximum trap fill time and number of microscans. Then, the analytical method was successfully validated. Finally, the method was applied for the determination of the antibiotic ciprofloxacin in the layers made from PEEK.
Keywords: Ciprofloxacin; liquid chromatography; magnetron sputtering; mass spektrometry; optimization; validation; Ciprofloxacin; hmotnostní spektrometrie; kapalinová chromatografie; magnetronové naprašování; optimalizace; validace
Citation: VACLOVÁ, Jana. Vývoj, optimalizace a validace analytické metody na stanovení antibiotika ciprofloxacin ve vodě pomocí LC/MS. České Budějovice, 2018. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/52432

Permalink: http://www.nusl.cz/ntk/nusl-382001


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses