Original title: Juvenile hormone signaling in insect development and reproduction
Translated title: Juvenile hormone signaling in insect development and reproduction
Authors: SMÝKAL, Vlastimil
Document type: Doctoral theses
Year: 2014
Language: cze
Abstract: This thesis comprises three published papers and one manuscript, all focused on the role of juvenile hormone (JH), the JH receptor Methoprene-tolerant (Met) and its target gene Krüppel-homolog 1 (Kr-h1) in insect development and reproduction. The JH-Met-Kr-h1 pathway is critical for metamorphic transition in hemimetabolan Pyrrhocoris apterus (Hemiptera) and holometabolan Bombyx mori (Lepidoptera) but seems to be dispensable during early larval postembryonic development. The results also show that Met and its heterodimeric partner Taiman (Tai) but not Kr-h1 are critical for ovarian development and vitellogenesis in Pyrrhocoris females. In vitro, in vivo and cell-based techniques in Drosophila melanogaster have demonstrated that Met and its paralog Gce are a bona fide receptor for JH. Only Gce capable of binding JH rescued Drosophila deficient for Met and Gce proteins, and the capacity of Gce to bind JH was necessary for JH-dependent transcriptional activation by Gce and Tai.
Keywords: bHLH-PAS; Hormonal signaling; Insect development; Insect metamorphosis; Juvenile hormone; Krüppel homolog 1; Metamorphosis; Methoprene-tolerant; Oogenesis; Vitellogenesis; bHLH-PAS; Hormonal signaling; Insect development; Insect metamorphosis; Juvenile hormone; Krüppel homolog 1; Metamorphosis; Methoprene-tolerant; Oogenesis; Vitellogenesis
Citation: SMÝKAL, Vlastimil. Juvenile hormone signaling in insect development and reproduction. České Budějovice, 2014. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/13953

Permalink: http://www.nusl.cz/ntk/nusl-177495


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Doctoral theses