Original title:
New potential antivirals against tick-borne encephalitis virus infection
Authors:
VESELKOVÁ, Barbora Document type: Bachelor's theses
Year:
2013
Language:
eng Abstract:
The experimental work of the thesis was concentrated on studying of the inhibition effect of twenty-six chemical substances on tick-borne encephalitis virus. The substances showing inhibition effect in High Throughput Screening assay were processed to Cytotoxicity assay, where their toxic effect on tissue cell cultures was determined. Subsequently, substances with inhibition effect and no cytotoxic effect were incubated with cell culture and virus in two different incubation time periods and the supernatant containing virions was examined using plaque assay.
Keywords:
Cytotoxicity assay; HTS assay; inhibition effect; Plaque assay; tick-borne encephalitis virus Citation: VESELKOVÁ, Barbora. New potential antivirals against tick-borne encephalitis virus infection. České Budějovice, 2013. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/27594