Název:
Exploration of 9-Bromo[7]helicene Reactivity
Autoři:
Žádný, Jaroslav ; Jakubec, Martin ; Velíšek, Petr ; Sýkora, Jan ; Storch, Jan Typ dokumentu: Příspěvky z konference Konference/Akce: 47. konference Pokroky v organické, bioorganické a farmaceutické chemii – Liblice 2012, Lázně Bělohrad (CZ), 2012-11-02 / 2012-11-04
Rok:
2012
Jazyk:
eng
Abstrakt: Our new microwave assisted photodehydrocyclisation and completely reviewed synthetic approach for a multi-gram scale production of 9-bromo-[7]helicene led us to explore the reactivity of this compound mainly in Pd-catalysed reactions and to the further functionalization of this molecule. Next to other transformations, palladium catalysed carbon – heteroatom coupling reactions provide a large portfolio of racemic helicenes bearing different functional groups in good to excellent yields. Many of the reactions are performed in the microwave initiator saving reaction time to a minimum comparing with conventional and known synthetic methods. Such prepared compounds can undergo further synthetic reactions or can be used on a field of molecular electronics, surface chemistry or in other applications. The separation of racemic mixtures is under running in our lab. Optically pure compounds of such a type can open new possibilities in their use.
Klíčová slova:
helicene; microwave synthesis; palladium cross-coupling Číslo projektu: GAP207/10/1124 (CEP), FR-TI3/628 (CEP), TA01010646 (CEP) Poskytovatel projektu: GA ČR, GA MPO, GA TA ČR Zdrojový dokument: Sborník abstraktů, ISBN N
Instituce: Ústav chemických procesů AV ČR
(web)
Informace o dostupnosti dokumentu:
Dokument je dostupný v příslušném ústavu Akademie věd ČR. Původní záznam: http://hdl.handle.net/11104/0217375