National Repository of Grey Literature 346 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
The role of intestinal microbiota in the development of Alzheimer's dementia
Hakenová, Kristina ; Valeš, Karel (advisor) ; Vodička, Martin (referee)
Preserving health at a higher age depends on the function of biological homeostatic systems (neural endocrine and immune activities), where the biological interaction between these systems and the intestinal microflora plays a key role. One of the most serious diseases associated with aging is Alzheimer's dementia (AD) and it is the most common cause of dementia in the world. This disease is accompanied by cognitive impairment associated with accumulation of amyloid plaques and neurofibrillary fibres in brain tissue. Naturally, biological changes occur during the process of aging, resulting in reduced functional capacity of the organism, accompanied by an increased risk of inflammatoryprocesses involved in the etiology of several chronic, pathologies, including neurodegenerative processes. These modulatory processes are associated with oxidative stress and intestinal dysbiosis. It is already well documented in the scientific literature that significant changes in the composition of intestinal microbiota occur in aging. These changes can lead to several biological changes, including increased permeability of the intestinal barrier, thereby causing the increased penetration of many biologically active substances into the body. This may be a risk factor for the development of inflammation in both...
Senior with hearing impairment and his quality of life
Gwoźdźová, Marie ; Hádková, Kateřina (advisor) ; Hradilová, Tereza (referee)
The diploma thesis focuses on the quality of life of seniors with hearing impairment. The thesis involves introduction into hearing impairment as well as its definition, occurrence and classification of hearing disorders. The etiology, diagnostics and hearing prosthetics are also included. The thesis also includes the issue of aging and the aging process, including social services and facilities for the elderly. The last chapter of the theoretical part deals with the quality of life, explains the established approaches, current models and methods of measurement. In the practical part of the thesis, a combined research was carried out. Data collection was carried out through semi-structured interviews with hearing impaired seniors as well as through questionnaires with experts in the field of ENT and phoniatrics. The aim of this research was to find out in which specific areas of the quality of life have the seniors recognized the largest decrease. Research questions were focused, for example, on the ways elderly people with hearing impairment deal with this disorder, on the choice of compensatory aids and on the degree of integration into society in dependence on the hearing impairment. KEYWORDS senior, retirement home, aging, hearing impairment, compensatory aid, quality of life, communication
Effect of regular physical exercise on metabolism of adipose tissue in elderly
Čížková, Terezie ; Šiklová, Michaela (advisor) ; Horáková, Olga (referee)
Ageing is associated with changes in body composition, which is caused by decreases in muscle mass and a progressive increase of fat mass. It is also associated with redistribution of adipose tissue with increased visceral and ectopic fat deposition. These changes are related to insulin resistance and other metabolic disturbances. Adipose tissue dysfunction is important contributor to the disturbed metabolic status of elderly and it is characterized by altered adipogenesis, metabolic flexibility and changes in secretory activity. Regular exercise is indisputably a key part of a healthy lifestyle. It was shown to improve muscle function, cardiovascular fitness and metabolic health of elderly. The aim of this thesis was to investigate whether a regular physical exercise can influence characteristics of an adipose tissue in elderly women, and if these changes in the adipose tissue can contribute to an improvement in an insulin sensitivity. In the two groups of elderly women, a long-term trained and a sedentary, the subcutaneous adipose tissue was analyzed for a gene expression of number of metabolic genes, an adipocyte size and a lipolytic rate at the basal state and after the isoproterenol stimulation. Anthropometric parameters and insulin sensitivity were also determined. Outcomes of this thesis...
Equality: age and gender (Czechia, Denmark, France, Poland)
Černá, Tereza ; Rychtaříková, Jitka (advisor) ; Kalibová, Květa (referee)
Equality: Age and gender Abstract Diploma thesis addresses age and gender inequalities in Czechia, Denmark, France and Poland, based on Special Eurobarometer 437 and Special Eurobarometer 465. It introduces basic terms connected with inequality in society as well as terms related to gender and age discrimination. The analytical part is focused on different perceptions of age and gender inequality by respondents from four selected countries. The questions are also analysed on base on the respondent's gender and their age group, either 25-34, or 55-64 years. The conclusion of the conducted survey data analysis is, that society in Czechia and Poland inclines towards gender-based prejudices and stereotypes more, than society in Denmark and France, which may be a consequence of stronger emphasis on gender equality in Western European countries. Age discrimination is more often noticed by Czech and French respondents, but it is clear, that respondents from all four countries perceive ageism as very serious and do not see adopted anti- discrimination measures as sufficient. Key words: discrimination, inequality, stereotypes, ageing, ageism, age discrimination, gender discrimination, Czechia, Denmark, France, Poland
Cellular senescence and ageing-associated diseases
Antoš, Šimon ; Hodný, Zdeněk (advisor) ; Horníková, Daniela (referee)
In the last years more evidence supports the role of cellular senescence in ageing-associated diseases. Cellular senescence plays a role in these diseases on multiple levels and often directly supports their pathogenesis. The goal of this bachelor thesis is to summarize latest knowledge regarding the mechanism and the efect cellular senescence has in ageing-associated diseases, namely cancer, atherosclerosis, osteoarthritis, neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and multiple sclerosis, obesity and diabetes mellitus type two.
Maintaining the positive effects of physical exercise programs for elderly several months after its completion
Smutná, Kateřina ; Daďová, Klára (advisor) ; Majorová, Simona (referee)
Title: Maintaining the positive effects of physical exercise programs for elderly several months after its completion. Aims: The main aim of this thesis is to detect, if the level of physical activity of seniors remain in existence even when the organized exercise program within the study EXODYA ends. Another aim is to discover a benefit of two exercise programs within one year in several selected areas. The last aim is to find out, whether the three months long exercise program will have a positive impact on physical and mental state of seniors. Methods: This is an empiric-theoretical research thesis. Three ensembles took part in a mixed qualitative-quantitative research. The muscle strength, flexibility, level of depressive signs and the state of short-term memory was tested with the ensemble I. (N=7) before and after an organized three months long exercise program. The testing of the ensemble II. (N=4) was held during the whole year (2018) within two exercise programs. The measuring of aerobic fitness and physical weight were added. The ensemble III. (N=31) were the alumni of the study EXODYA and they participated in the self-designed survey, where they were asking about the recent level of physical activity. Results: Positive effects were noticed during the three months long exercise program....
Animal Asisted Activity and Animal Assisted Therapy in Context of Social Services
This bachelor thesis maps the provision of activities and therapies with the assistance of animals in the kontext of social services. It deals with activities and therapies assisted by animals in the Retirement home TEP, the center of social services in Veselí nad Lužnicí and examines the benefits of activities and therapies for its users. There are defined old age and aging, retirement home, activities and therapies assisted by animals, thein contribution for retirement home and organizations operating in this area. The practical part of this thesis consists of research. Its main goal was to map the provision of activities and therapies with the assistance by animals in the Retirement home TEP, the center of social services in Veselí nad Lužnicí. The qualitative research strategy, the method of questioning and the technice of semi-structured interviews were choosen. Participant observations and secondary data analysis were also used. The research group consisted of five users who used animal-assisted aktivity and therapy for more than 1 year and were over 65 years old. The results were processed into case studies. The research shows that activities and therapies assistanced by animals in the retirement home take the form of a visitor and resident program. Users can see the benefits of animal in improving their mental condition, communication with employees, practicing memory and fine and gross motor skills. Most of the pensioners think that this therapies has no straight impact on making new friendships. This work can be used primarily by retirement home workers who practice animal-assisted activities and therapies to bendit users. Finally it can help bring this activities and therapies closer to the general public.
Změny v telomerázové aktivitě u dlouhověké zimní generace dělnic včely medonosné (\kur{Apis mellifera})
BREJCHA, Miloslav
Telomerase activity was compared between the long-lived winter generation and the short-lived summer generation of Apis mellifera workers. Transcription levels of endocrine signaling determinants associated with aging were compared between these generations. Effects of photoperiod and egg laying rate on the telomerase activity of the winter generation of honey bee workers were tested.
Properties of polymer modified bitumen for warm mix asphalt
Zábranský, Ivo ; Koudelka, Tomáš (referee) ; Dašek, Ondřej (advisor)
The Diploma thesis is focus on polymer modified bitumen for warm mix asphalt. The theoretical part of the thesis describes additives which influence the properties of bitumen for their use and reduction of production and service temperatures. Further, the theoretical part describes the conclusions from the researches. This part also describes empirical and functional tests of bituminous binders. The practical part presents the results of individual tests. Tests were performed on samples of non-aged, aged by RTFOT and RTFOT + PAV methods. The results of the work and the assessment of the suitability of bituminous binders are summarized at the end of the thesis.
Leisure activities of seniors in retirement home
The aim of this bachelor thesis is to describe the area of offered leisure activities and their connection with individual planning. The bachelor thesis contains 6 chapters. The first part describes the old age, aging and age-related changes. It also describes social services, the above mentioned leisure activities, quality standards of services and individual planning. The fifth chapter focuses on Home for the Elderly in Strakonice. It presents basic information about this facility, describes individual planning and leisure activities in the Home for the Elderly in Strakonice. The last chapter is devoted to the research survey us in the method of content analysis. The aim of this research is to find out to what extents the offered free-time activitie correspond with activities in individual plans of seniors in the Home for the Elderly in Strakonice. The research results show that this facility provides a lot of leisure activities that agree with activities described in the IPs of seniors.

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