National Repository of Grey Literature 177 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Epilepsy impact on quality of life in women
Prudnikova, Elizaveta ; Lustigová, Michala (advisor) ; Špačková, Petra (referee)
This thesis looks into the concept of the quality of life in women with epilepsy from a qualitative perspective. Epilepsy, as is a chronic neurological disease, affects not only everyday activities after the diagnosis, but also has its impact on the women's life regarding employment or family. By adapting the narrative analysis this thesis categorizes the influential factors of this concept into primary and secondary ones. Moreover, it explores in detail the issue of obtaining a driving license, which is one of the specifics of the people with epilepsy in Czechia. Also, it defines the respondents' attitudes toward the societal perception of epilepsy and fears that accompany it. In addition to that, the matter of motherhood and pregnancy for women with epilepsy is explored as one of the influential factors of the quality of life. Lastly, this thesis argues that the qualitative approach is essential for the initial examination of the selected sample for future investigations regarding the concept of the quality of life in epilepsy.
Clinical and nursing aspects of patients treated surgically for HPV-related ofopharyngeal tumours
Báťová, Linda ; Zábrodský, Michal (advisor) ; Jankovcová, Kateřina (referee)
Introduction: Oropharyngeal tumours belong to the most common malignancies situated in the head and neck area. In the past, their incidence has been associated with classical risk factors (smoking and alcohol use). In the recent years, the increase of oropharyngeal carcinomas resulting from HPV (human papilloma virus) infection incidence has been observed. The change of their aetiology also implies a number of clinical differences, the most important being a significantly better survival prognosis in patients with HPV+ carcinomas. Aims: The main goal of this thesis was to characterize correctly patients with oropharyngeal carcinomas and to identify different specifics of nursing intensive care for these patients. Methods: The quantitative prospective study involved 30 patients following their surgical treatment of oropharyngeal carcinoma, hospitalised in an intensive care unit. The patients were divided into 3 groups: HPV+ non-smokers, HPV+ smokers, HPV- smokers. Results: The study confirmed the demographic differences between individual patient groups. The HPV+ non-smokers group is characterized by a lower age in average, which is significantly reflected in a reduced duration of hospital stay. In addition, opioid administration rate, infection rates and postoperative complications incidences are...
Basic stochastic epidemic models
Strachoňová, Karla ; Hudecová, Šárka (advisor) ; Kulich, Michal (referee)
This thesis deals with two basic models which are used for epidemic model- ling in closed populations, namely Greenwood and Reed-Frost models. At first, knowledge which a reader needs to have about Markov chains and random varia- bles is summarized. Then the two models are described by modelling the number of susceptible and infectious individuals, as well as the duration and size of the epidemic. All of these approaches to modelling an epidemic are then illustrated on examples. Finally, the maximum likelihood method of the probability of infection is described and illustrated on real data in the last chapter, where the obtained results are discussed as well. 1
Risk factors affecting endometriosis in women of reproductive age, ALSWH Study
Olšarová, Karolína ; Dzúrová, Dagmar (advisor) ; Pikhart, Hynek (referee)
This thesis adapts a life course approach in epidemiology to endometriosis. Endometriosis is a highly prevalent chronic disease affecting women in reproductive age. Firstly, the topic of this disease is introduced, the situation and current knowledge in Australia is discussed. Positive changes in a national level are presented. Secondly, early life exposers and maternal behaviour are investigated as possible risk and protective factors. A systematic review of early life factors identified a low birthweight and formula feeding of infants as risk factors for the development of endometriosis. Lastly, the relation of birthweight, weight at childhood and endometriosis was analysed using data of Australian Longitudinal Study on Women's Health. Other risk and protective factors were evaluated and included into the analysis. Logistic regression was used for determination of statistical significance. High weight at 10 years old was found to be a protective factor against endometriosis.
Epidemiological and ecological impacts of floods in the Cesky Krumlov district
PAPOUŠKOVÁ, Michala
The topic of my diploma thesis are Epidemiological and ecological impacts of floods in the Cesky Krumlov district. In the theoretical part I deal, from the perspective of epidemiology, with infectious diseases that may occur due to floods, I explain what information system was used by the regional hygiene stations in order to carry out the obligatory report, records, and analysis of occurrence of infectious diseases, and I would like to point out that from 1 January 2018 on, a new system started working for regional hygiene stations in the Czech Republic. Further, I deal with ecological impacts, and explain ecology in terms of Nature Conservation Act. Last but not least, I mention floods as such in the theoretical part, I define flood legislation, what administrative authorities work if such a crisis situation occurs, and what flood affected the region of Cesky Krumlov. The practical part analyses Epidat and the ISIN information system data using metaanalysis, searching for a link between them and infectious diseases during floods. I focused on infectious diseases that ma occur in connection to floods, such as Leptospirosis, Shigelosis, Cryptosporidiosis, Gastroenteritis caused by Campylobacteria and Norovirus, Virus Hepatitis type A, and Virus Hepatitis type E. The Discussion part evaluates the questionnaire aimed at the citizens of Cesky Krumlov region, also at the primary school pupils. What is their image of consequences of floods, and what may bet he cause. The results are then discussed in the conclusion of my diploma thesis. Creating an information leaflet meant for the lay public is another output of my diploma thesis.
Epidemiological Situation at a Pharmacy.
SCHNEIDEROVÁ, Kateřina
Airborne respiratory infections are among the most frequent diseases. Airborne respiratory infections afflict both children and adults; they can pose a potential threat to persons already suffering from another primary illness or those with impaired immunity. A disease-carrying person transpires pathogens through droplets or biological aerosol when coughing, sneezing or talking. Such ways of illness transmission pose a risk of nosocomial infection dissemination in medical facilities. The objective of this Bachelor's thesis is to quantify microbiological pollution in the indoor environment and evaluate the negative influence, if any, of bacterial contamination on the health of patients occurring at the pharmacy. The laboratory work part of the thesis aimed at the sampling, processing and identification of airborne infection agents at a medical facility (pharmacy) in the period of May 2018 to February 2019. The sampling method used was the method of passive collection (platform settling method). The principle of this method is that microorganisms present in the air settle over blood agar in a Petri dish. The factors evaluated in analyzing microbiological pollution of indoor air included the influences of air temperature and humidity at the pharmacy, as well as the number of persons present at the time of taking the sample. Pursuant to Decree n. 6/2003, which sets hygienic limits for biological indicators in indoor environments of frequented premises in medical facilities, the maximum limit is 500 CFU/m3 (CFU is a unit used to estimate the count of viable bacteria). The counts found during the review period have never reached the limit. The values measured showed that there is a certain degree of positive correlation between the air temperature, air humidity and CFU count per dish. Comparisons between the number of patients and the CFU count per dish demonstrated no distinct cross-correlation between the two factors. As far as the representations of individual groups of identified microorganisms in the samples are concerned, the G+ Staphylococcus spp. group takes a prevalent share, counting for more than 50 % of microorganisms in the samples, and as much as 75 % in some samples. G- rods follow, with a share of as much as 46 %, further followed by G+ diplococcus and tetracoccus bacteria with a share of as much as 43 %. Of the focus pathogens, the occurrence of Staphylococcus aureus and Streptococcus pyogenes were confirmed. The results of my bachelor's thesis did not confirm any overlimit microbiological pollution of the pharmacy indoor air or a significant occurrence of bacterial respiration infection agents. In conclusion, in terms of bacterial contagion, indoor air at pharmacies can be seen as a low risk.
Epidemiology of sporadic forms of colorectal cancer in terms of preventions and the possibility of early diagnostic.
Schneiderová, Michaela ; Bencko, Vladimír (advisor) ; Krška, Zdeněk (referee) ; Hudečková, Henrieta (referee)
Thanks to the latest achievements in diagnostics, surgery and oncology, the overall perspective of colorectal cancer has changed significantly. There are no doubts that we deal with a complex disease, requiring multidisciplinary approach and assessment. Only this approach can enable patients to survive longer and maintain acceptable quality of there lives. Taking a long view over several decades, the steep rise in incidence of this malignancy was strongly alarming. It is partly a penalty for a prolongation of life expectance, since one of the risk factors is age. Knowing the way of life and dietary customs of our ancestors, one cannot deny that the change of lifestyle including dietary habits, as well as decrease of physical activity, obesity, stress, unsuitable thermal processing of food produced in bulk, consumption of immoderate amount of red meat, limited intake of raw vegetable and fruits, excessive intake of xenobiotics, such as medication or cosmetic products, excessive alcohol consumption, particularly beer, nicotinism, environmental pollutants, etc. contribute to the increase of this cancer incidence. All the above mentioned factors have led over the time to a formation and development of numerous so called civilization diseases, among which rates the colorectal cancer (CRC). Despite the...
Extensively resistant Acinetobacter baumannii in the Czech Republic: population genetic structure and mechanisms of resistance to carbapenems and aminoglycosides
Švandová, Ladislava ; Nemec, Alexandr (advisor) ; Melter, Oto (referee)
This study focuses on the question of the epidemiology of resistance to antibiotics in Acinetobacter baumannii, which is nowadays one of the most problematic bacterial patho- gens associated with failing antimicrobial therapy. Its aim was to define population-genetic properties, epidemiology and the nature of multidrug resistance for a sample of the current population of A. baumannii from Czechia. A total of 55 isolates were collected in eight medi- cal facilities in central Bohemia from October 2016 to May 2018. The isolates were assessed for their identity at the species, clonal and strain levels as well as resistance phenotype and genotype; they were classified into five clonal groups, each of which encompassed isolates that were likely to be epidemiologically related. The 55 isolates studied belonged, nearly exclusively, to global clone ECII, with 53 % of them forming a genetically relatively homoge- neous group characterized by extensive resistance to antibiotics (susceptible only to col- istin), the presence of genes encoding ArmA a OXA-23 (resistance to all aminoglycosides and carbapenems) and spread in all locations. The in-depth epidemiological analysis of isolates from the city of Příbram and its vicinity indicated the regional spread of two strains, one of which belonged to the...

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