National Repository of Grey Literature 45 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Reakce neuroendokrinního systému koní na stres
Šimková, Daria
ŠIMKOVÁ, D. Reaction of Horse´s Neuroendocrine System to Stress. Mendel University in Brno, 2017. Bachelor thesis. The bachelor thesis deals with the issue of stress in connection with neuroendocrine systems. The work is focused on the comparison and cooperation of these two systems depending on the stress. The first part describes general characteristics of the endocrine system and hormones, a general description of the nervous system and the definition and view of stress. In the next part are given the specific organs of the given systems and their main function. End of the chapter is devoted to the pathological processes of both systems. In conclusion the effect of stress on these systems and the impact on possible desorders and diseases of the neuroendocrine system are summarized.
How does the fluid intake affect the gastrointestinal absorbtion of levothyroxine.
Kročová, Radka ; Krátký, Jan (advisor) ; Hána, Václav (referee)
Thyroid diseases belong among the most common endocrinopathies, and, therefore, thyroid hormones are among the most commonly prescribed drugs in the Czech Republic, as well as in the world. Even though untreated thyropathies may cause several health complications for the patients, poorly administered treatment can also hurt the health of the individual. Several factors make the treatment difficult. A type of fluid used to ingest the drug belongs among such factors, and it represents the focus of this Master thesis. As is indicated by its title, the thesis focuses explicitly on the gastrointestinal absorption of levothyroxine after being ingested with water, black tea or cow's milk. The thesis was aimed at determining whether and to what extent, if any, the fluids may influence the gastrointestinal absorption of the drug. Based on this premise, research was conducted with six test subjects who underwent a relatively challenging absorption test with four blood samples taken over six hours. The data set (altogether 56 samples taken from all test subjects) had revealed that the gastrointestinal absorption of levothyroxine reached its maximum values when the drug was ingested with water. The other test fluids impair the bioavailability of L-thyroxine, and patients should wait to indulge in them at least...
Accumulation 99mTc-pertechnetate in the thyroid gland
BARTOŠ, Štěpán
The objective of this bachelor thesis is to answer the following research question: "What is the extent of normal values of Technetium-99m accumulation in the thyroid gland?" I gained the answer by collecting data and subsequently assessing results of static scintigraphy of thyroid gland examined in 34 patients at the Department of Nuclear Medicine in the hospital Nemocnice České Budějovice. The reference file of patients was collected from January to December 2017. On the basis of clinical data on the examination request form, the supervisor excluded results that showed symptoms of hypothyroidism, hyperthyroidism or thyroiditis. The anatomy and physiology of the thyroid gland and parathyroid glands are described in the introduction of the theoretical part of the bachelor thesis. The following chapter characterizes thyroid disorders. The last chapter describes the examination of thyroid gland using methods of nuclear medicine, check-up, radiopharmaceutical drugs used and making and processing an image. The practical part describes the procedure of elaborating my bachelor thesis at the Department of Nuclear Medicine in the hospital Nemocnice České Budějovice. There I worked with evaluating computer program Xeleris with the Thyroid Uptake Index application. I plotted the region of interest around the thyroid gland manually and calculated the value of accumulation in the thyroid gland with a programme. I processed the gained values statistically using formulas to count the average, standard deviation and percentile in Microsoft Excel. I fixed the percentile for 10 % and 90 %. Calculations show that a normal value of Technetium-99m accumulation in the thyroid gland ranges from 0.4 % to 1.8 % and the average is 0.85 %. This work can serve as evaluation of normal values of accumulation during examining thyroid gland at departments of nuclear medicine.
Relationship of body composition to endocrine orbitopathy
Nová, Veronika ; Hána, Václav (advisor) ; Krátký, Jan (referee)
In the theoretical part I briefly introduce the reader to the current state of given topic and describe the function of thyroid gland, how much important it is for our organism and also the possible influence of nutrition on this organ. The next chapters discuss endocrine orbitopathy. Endocrine orbitopathy is a chronic ocular disease, which is frequent in patients with Graves - Basedow disease. I focus not only on the epidemiology and causes of the disease, but also on assessing the severity and treatment of endocrine orbitopathy. The practical part focuses on eating habits and lifestyle of patients with endocrine orbitopathy and assesses the possible effect of body composition on endocrine orbitopathy. At the same time, 4 hypotheses were established. The first hypothesis assumed that higher % body fat and higher BMI may influence the course of endocrine orbitopathy. The second, that nicotine-dependent patients with endocrine orbitopathy predominate over individuals who do not use this addictive substance. In the third hypothesis, I assumed that patients with endocrine orbitopathy would have another associated civilization diseases. And the last, the fourth hypothesis compared the effect of fish consumption on the level of selenium in the blood. To collect data, I used questionnaires inquiring...
Thyroid gland of calves
GRÉK, Miloš
There were thyroid glands of 4 calves examined in this work. Calves were of the Holstein breed and were observed during the first 3 months of their life. Investigated parameters included levels of thyroid hormones and their relation to TSH, age related changes in Ca, Mg, P, protein, urea, triglyceride and gamma-glutamyltransferase (GMT) levels in blood plasma, length, width and perimeter of follicles and height of follicular cells. Mean total T4 content was 72,56+-17,76 nmol/l, T3 3,22+-1,04 nmol/l and TSH 0,94+-0,32 ng/ml. There was a positive correlation between the hormones and their free forms, and between T3 and TSH. T4 level rose with age, while T3 level fell. Protein and urea content rose with age as well, triglyceride and GMT content dropped. Ca, Mg and P content was relatively stable during the whole experiment. A higher number of small and medium sized follicles were observed in the thyroid glands. Mean follicle length was 86,24+-45,36 microns. Follicular cells reached a mean height of 7,95+-1,30 microns. All of the follicular parameters were highly individual, except follicular cell height.
Nursing caring for a patient with thyroid gland disease
Drnek, Jan ; Pírková, Vendula (advisor) ; Kulhavá, Miluše (referee)
This bachelor's thesis "Nursing care for female patient with thyroid disease" consists of two parts describing theory and practise. Theoretic part provides basic information about thyroid gland - anatomy, histology and physiology - function in human organism, followed by description of goitre, the most frequent disease requiring surgical intervention, focused on disorder reasons, incidence symptoms, diagnostics, therapy, possible complications and prognosis for patients suffering this disease. Part of the literary researche describes the nursing care process for patient with planned neck surgery, and the role of the nurse in pre- operative preparation and a post-operation care. Practical part presents a case story of 53 years old female patient from diagnosis to definitive surgical solution. Case story has been described according to the Marjorie Gordon nursing modus, which accentuates biologic and social needs of the client. After presentation of basic data on patient, diagnostics and therapy of her disease and hospitalisation course, the story has been focused on specific needs of the client, formulation of nursing diagnoses, targets and plans, their realisation and evaluation. The aim of this thesis was description of question is in surgically intervented thyroideal disease focused on nursing...
Thyroid tumors and their molecular genetic causes.
Šmídová, Barbora ; Dvořáková, Šárka (advisor) ; Soták, Matúš (referee)
The aim of this work is to summarize actual literature overview and to collect the up- to-date knowledge on genetic causes of the development of thyroid carcinomas. Thyroid carcinomas represent the most often endocrine malignancy and its incidence is still growing. This work describes all types of thyroid carcinomas derived from different cell types and are distinguished also according to the degree of differentiation. The main genetic changes in the tumor tissues of the medullary, papillary, follicular and anaplastic thyroid carcinoma are described. Thyroid carcinomas occur mostly in sporadic form, rarely as a familial disease. The causes of familial forms of thyroid carcinomas are also summarized and the main mutations in the germ-line DNA are identified. Key words: carcinoma, genetics, mutation, thyroid
Thyroid tumors and their molecular genetic causes.
Šmídová, Barbora ; Dvořáková, Šárka (advisor) ; Koudelková, Lenka (referee)
The aim of this work is to summarize actual literature overview and to collect the up- to-date knowledge on genetic causes of the development of thyroid carcinomas. Thyroid carcinomas represent the most often endocrine malignancy and its incidence is still growing. This work describes all types of thyroid carcinomas derived from different cell types and are distinguished also according to the degree of differentiation. The main genetic changes in the tumor tissues of the medullary, papillary, follicular and anaplastic thyroid carcinoma are described. Thyroid carcinomas occur mostly in sporadic form, rarely as a familial disease. The causes of familial forms of thyroid carcinomas are also summarized and the main mutations in the germ-line DNA are identified. Key words: carcinoma, genetics, mutation, thyroid

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