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Men's awareness about the issue of testicular cancer.
POSPÍŠILOVÁ, Markéta
Theoretical solution Testicles are the primary male sexual organs producing testosterone. They not only make sperm but also secondary sexual features and the whole personality. We should mainly pay attention to testes in oncology because there are more occurrences of tumors with the men of younger age. These men might be very sensitive about the problems concerning sexual system and that is why the bachelor thesis deals with the issues of men's knowledge of testicular cancer. There is basic information in the thesis about organs anatomy, factor of disease, diagnostics and medical treatment. The thesis is further focused on secondary preventive measures and method of self-examination of testicles. It helps to recognize the problem in time which is in this kind of cancer very crucial. There is also mentioned the role of nurses and their instruction to men about the prevention of testicular cancer, medical care of the patient during the diagnostics, pre-operative preparation, postoperative care and other healing process. Aim of the Thesis Aim 1 Find out how much men are aware in the field of testicular cancer? Aim 2 Find out the change of behavior of men to their health after the operation of testicles? Research Question n. 1 How much men are aware about the problem in their risk age? Question n. 2 How much men are aware of self-examination methods? Question n. 3 In what field has changed the men's behavior to their health after the operation of testicles? Methodology To be able to find out necessary data, qualitative method was picked. To the collection of information was used method of half-standard interview with the questions to the concrete issues. Five respondents in a risk age were approached to the research in the case of malignant tumors origin on testicles and five respondents who had already undergone the treatment of this disease. Information was analyzed, consequently put to the categories and finally evaluated. Results Results of the research showed that men are mostly aware of the problems of testicular cancer. They usually underestimate this disease because they are not informed about the issue enough. Men usually know about the symptoms but most of them have wrong idea about the age occurrence and medical treatment. Preventive method of self-examination is for men usually unknown. Respondents who underwent operation of malignant tumor of testicles are about this method properly instructed. Frequently, according to the results, they make light the return of the disease and also do not practice the self-examination method regularly. Results also revealed that this disease is still somehow a taboo. Some respondents with the successful cure admitted that they were ashamed for this diagnoses. Conclusion The research showed us that men are not informed enough about the malignant tumor of testicles. This also confirms the fact that healthy men do not know the self-examination method. According to the results men who underwent the treatment of testicular cancer are now more informed but they usually underestimate the necessity to do the self-examination regularly. They also admitted in the interview that they were not informed enough before the disease. If they were, their health problem could have been discovered earlier and the high risk of metastasis could have been lower. For all this there is a need to increase the knowledge of the malignant testicle tumors in population which will influence the regular usage of self-examination method and it can also change the attitude of men to their health. Bachelor thesis contains pamphlet about the origin of testicular cancer. It is intended for men who are in risk age and it will be offered as a practical usage in medical facility.
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The System of Employee and Development in a selected organization
MOTEJLOVÁ, Lucie
The topic of the diploma thesis is focused on the areas of human resources management, education and development of employees in a Fire Rescue Brigade of South Bohemia. The principal aim of this thesis was the evaluation analysis of the system of employee education and development in the selected company, identification of educational needs, proposals for changes and recommendations for improving the management of this area.
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In vitro expansion and activation of natural killer cells for cell therapy.
BENEŠOVÁ, Monika
NK cells are part of the non-specific immune response and are one of the main components of antitumor immunity. They do not need antigen stimul for thein activation but recognize damaged ( transformed ) cells by characteristic decreased expression of MHC I molecules. These natural killers become subjekt of many clinical studies based on the use of anti-tumor activity of NK cells for both solid tumors and in hemato - oncological diseases. The aim of this study was to find optimal conditions for in vitro expansion and activation of NK cells. NK cells were isolated from mononuclear cell fraction by magnetic separation and cultured in two types of media SCGM and X - VIVO 10 with the addition of interleukin-2 respectively OKT3 antibody. The influence of the mononuclear cells on proliferation of NK cells was tested. After a 6- day culture , the cells were passaged and growth of NK cells was determined using hematological analyzer and flow cytometry. Expression of the activation markers CD25 and CD336 (NKp44) was observed. All experiments were conducted under conditions of good manufacturing practice. Slightly higher gain of NK cells was observed in SCGM media without a significant differences in the other additives. Much higher number of NK cells was observed in culture with supporting irradiated mononuclear cells. There were no differences in cultures with autologous or allogeneic cells. We found that NK cells with higher proliferative potential express increasingly CD25, unlike the cells with decreased proliferation which had increased expression of CD336 marker. The work led to the definition of the optimal culture conditions for NK cells and became the basis for the further development of the medicinal product from in vitro activated NK cells.
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Evolution of social perception of people with handicap in Grade school for children with special needs of teaching
MITÍSKOVÁ, Jana
Title of the thesis: The target of my dissertation is the qualitative research based on grounded theory in which I am trying to detect the development of social perception of disadvantaged pupils at ?Základní škola praktická? in Milevsko. In the theoretical part I am giving a definition of terms ? social perception, perceptions´mistakes, stereotype, labeling, stigmatization, communication, mental handicap and memory, episodic memory and autobiographical memory. The target of the methodical part is to clarify the basics of grounded theory by using the methody of half-structured depth interview and observation. After implementation of qualitative research I want to summarize the discovered patterns of social perception and to find the movements in the field of social stereotypes in the specialists´approach to disadvantaged pupils.
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The methodics of plant nutrition and fertilization by phosphorus
Kunzová, Eva
The methodics inform about situation in plant nutrition and fertilization by phosphorus on arable soil in Czech Republic. The methodics indicate two approaches for assessment of fertilization demand utilized as well for checking of phosphorus input limits requested by different legislation. There is evaluated need of phosphorus for expected production and soil fertility stabilization.
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Cooperation with clients´ families in the Retirement Home Třebíč during the period of adaptation process
DOLEČKOVÁ, Olga
In the Bachelor´s Thesis I devote my attention to the issues concerning adaptation process of a senior starting in a long - stay social service - the Retirement Home Třebíč - in connection with cooperation with family members. The issues regarding old age, the elderly in need of help from others, are becoming more and more important in today´s society. This fact is closely linked with the increase in human life span. In the theoretical part I defined the terms: old age, age division, and the changes that take place in this inherent developmental stage of life. In addition, I dealt with the active process of adaptation to novel living conditions, and the symptoms of maladaptation. In the following chapter I described a family, its functions in today?s society, and the family relationships. I defined social protection and social services set in the legislative frame, as well as problems regarding registration of social services. I described the Retirement Home Třebíč, where the research took place, and the process of individual planning, whose component user´s adaptation is. The way in which adaptation takes place, how often and the manner in which family members cooperate with a senior and the staff of the organization is very important during this period. I devoted the research part of my Bachelor´s thesis to this particular area. In order to describe the cooperation I used qualitative research with the method of questioning, the technique of a semi-structured interview. There were eight respondents; family members, instructors of social services, and key workers, participating in the research. The results confirmed that a family´s cooperation proves to be a key area when looking into adaptation in a retirement home. If a family does not cooperate or in case of a lonely senior, this role is to be supplemented by staff of the retirement home. It is up to them whether they can eliminate the potential impact of social maladaptation on the senior. The results of the research confirmed that it is important to support cooperation between families and the users of social service, so that a life in a retirement home resembles the one in a natural environment before their arrival as much as possible.
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Conditions and learning opportunities for students with disabilities at the University of South Bohemia
VLKOVÁ, Lucie
The Bachelor thesis deals with the conditions and learning opportunities of tertiary education for students with disabilities at the University of South Bohemia. In the theoretical part I define basic themes regarding disabilities, types of disabilities and etiology and classification os disability. Next I dedicate tertiary education for students with disability at universities, specifically at the University of South Bohemia. In the practical part I set a goal to specify conditions and learning opportunities, which University of South Bohemia provides for students with special educational needs. I chose a qualitative type of research and the technique of semi-structured interview. I address five students with disability, whose are studying on the various faculties of the University of South Bohemia and I asked them the same questions. Research evaluation results can be used as recommendation for the practice. Acquired knowledge about specifics of tertiary education students with disability may have serve to potentially innovation opportunities, which the university provides and for expansion universal opinions and important information.
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Analysis of the Situation of CHildren Aged 0-6 Years Growing up in Residentional Homes in the Region Vysočina
FÁROVÁ, Jana
In the Czech Republic, about one per cent of children grow up outside their own families, mainly children under the age of three. For this reason the Czech Republic has lately received several important challenges concerning a fundamental reform of the children at risk care system. The aim of my thesis was to carry out an analysis of the development and changes in the comprehensive care and in the situation of the children in the Children?s Centre Jihlava and in the Children?s Home Kamenice nad Lipou in the years 2005, 2010 and 2011 in chosen aspects. The research was focused on changes over time in the situation of concrete children?s homes, further on the changes in the provided care depending on the children?s characteristics and specific needs, and finally on the changes in the cooperation with the biological families and in the circumstances how the stay of children is terminated. To achieve these goals of my thesis, a secondary data analysis and SWOT analysis was carried out. Two files were analysed recording the situation in the Children?s Centre and in the Children?s Home during the the years 2005, 2010 and 2011.
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