National Repository of Grey Literature 271 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Genetic factors in the etiology of migraine
Skoblíková, Daniela ; Šolc, Roman (advisor) ; Mravec Bencúrová, Dominika (referee)
Migraine is a chronic condition with a significant prevalence in the human population- Its aetiology involves a combination of both environmental and genetic factors; however, the primary cause is still not entirely clear. The pathophysiological mechanism of the brain, which forms the basis of migraine aura, is considered to be a transient wave of neuronal depolarization in the cortex, known as cortical spreading depression (CSD). Despite considerable discrepancies, there is a wealth of information on suspected or already identified genes whose mutations could potentially be responsible for initiating the migraine state. Currently, there are three recognized responsible genes that have been identified through classical linkage analysis. All three known FHM mutations encode mechanisms that affect ion transporter: the CACNA1A, ATP1A2, and SCN1A genes. Their dysfunction ultimately leads to an increase in neuronal excitability. Pathogenic variants in other genes, such as PRRT2, PNKD, SLC2A1, SLC1A3, SLC4A4, and KCNK18, have also rarely been found in HM. Keywords: migraine, genetic factors, pain, aura
Individual possibilities of involvement of relaxation techniques in rehabilitation care of patients after implantation of a total hip joint endoprosthesis
Gallová, Iveta ; Strnad, Pavel (advisor) ; Mahrová, Andrea (referee)
Title: Individual possibilities of involving relaxation techniques in the rehabilitation care of patients after implantation of a total hip joint endoprosthesis Objectives: The goal of the thesis is to offer to individual probands the possibility of including relaxation techniques in therapy, beyond the scope of normal rehabilitation after implantation of a total hip joint endoprosthesis. Methods: The diploma thesis is of a theoretical-empirical nature and is conducted as qualitative research. The monitored group consisted of 4 people - 3 women and 1 man, aged 50 to 55 years, all after primary implantation of a total hip joint endoprosthesis, who were hospitalized in the hospital's rehabilitation department for 3 weeks. The research part of the thesis was focused on the inclusion of exercises with elements of relaxation techniques in the therapy of individual probands. The intervention was an individually designed exercise using elements of relaxation techniques for individual probands. The structure of this exercise changed during the research depending on the fitness of the probands and their current physical and psychological state. The following methods were used for data collection: semi-structured interview, taking anamnesis, inspection, palpation, measurement of joint ranges according to the...
Psychological aspects of pharmacological pain management in palliative care
Trefná, Klára ; Niederlová, Markéta (advisor) ; Šivicová, Gabriela (referee)
This thesis deals with the psychological phenomena that are associated with the pharmacological pain management in a context of palliative care. The issue involves patient himself, but also a caregiver and a medical staff. The theoretical part of this thesis deals with pain and pharmacological pain management from a psychological point of view and focuses on a problematic attitude toward opioids. This thesis is based on the latest scientific findings by Czech and international researchers. This thesis also includes a research plan, which deals with the psychological factors that affect the attitude toward opioids in Czech environment.
Pain in patients with multiple sclerosis
Paulů, Kateřina ; Novotná, Klára (advisor) ; Grosserová, Barbora (referee)
The bachelor thesis deals with the topic of pain in patients with multiple sclerosis. The aim of the thesis is to map the prevalence of pain among patients with multiple sclerosis, its localization, time course, triggering factors, type, character, intensity and some other aspects pain through a shortened Czech form of the standardized questionnaire of McGill University. The thesis consists of theoretical and practical part. The theoretical part deals with the issue of pain in general, but also focuses on the individual types of pain that are characteristic of multiple sclerosis. The practical part relies on data collection by means of a questionnaire survey that focuses on mapping the prevalence of pain, its location, haracter, duration, intensity and other possible related factors. To collect data, I used a shorter form of the Czech version of the standardized McGill University questionnaire. The questionnaire survey was carried out with patients of the Centre for Demyelinating Diseases, Department of Neurology 1. LF UK and VFN in Prague, who were given a paper questionnaire. The information I obtained was processed into graphs and tables. The results showed that pain is present in 60 % of respondents with multiple sclerosis, most often localized in the spine and lower limbs. The intensity of...
Hospital
Vlachová, Sandra ; Písaříková, Jana (referee) ; Kvíčala, Petr (advisor)
My Bachelor's thesis is called Hospital. It contains my memories, that I written down during my hospitalization, and then brought to life on the canvas. The main theme are the painful thoughts that ran thought my mind while I was in the hospital. My thesis presents a diary record, which serves as a main source of inspiration for my paintings, as well as a technical record. The main point of my thesis is the subsequent trauma - dealing with the scars, accepting yourself. From the beginning of my studies, I have been devoted to the motifs of architecture, clean and clear colors with fine lines and geometric shapes. My work was very precise and delicate. Now I present the theme of the hospital, connecting my interest in architecture with more personal themes. My stay in the hospital, trauma, and pain. Which reminds me of the book Umlčené tělo (Murphy 2001), which contains and incredible story about the author's life before and after his illness. This book has been a great inspiration to me.
Factors affecting prevalence of pain among European population
Míšková, Markéta ; Lustigová, Michala (advisor) ; Žejglicová, Kristýna (referee)
Pain is a part of many people's lives and can also affect them in significant ways. This paper examined various factors that are related to the prevalence of pain in the European population. The aim was to identify these factors and describe the differences between the population groups. The analyses involved individuals aged 20 years and older who participated in the 2019 European Health Interview Survey. The association between selected demographic, sociodemographic and socioeconomic factors, as well as between lifestyle factors and pain prevalence, was analyzed using chi-square tests and binary logistic regression. Attention was also paid to the relationship between mental health and pain prevalence. It was found that women are more prone to the occurrence of pain as well as persons of advanced age. Although married people show a lower risk of suffering from pain, the impact of living with a partner on the incidence of pain is quite contradictory. The association between this variable and pain prevalence varies depending on control variables. More educated persons are less likely to report prevalence of pain. In turn, unhealthy lifestyle activities, other than alcohol consumption, are considered to be risk factors. Also, individuals with severe symptoms of depression have a higher likelihood of...
"It's just a state of mind" - An Ethnography of Pain and Injury Among Elite Athletes
Korečková, Adéla ; Halbich, Marek (advisor) ; Poděbradský, Oldřich (referee)
The main topic of this thesis is pain and injury. The research on these two phenomena, which are closely related to elite and high performance sports, was conducted in the environment of a training group of elite athletes - throwers. The aim of the thesis is to describe how these researched athletes react and how they experience pain and injury. Pain and injury are two distinct concepts that may or may not occur together. Pain is a more subjective phenomenon, whereas injury tends to be viewed more objectively. Athletes test the limits of the human body in training and competition, and it is very common for both of these phenomena to occur. A culture of risk-taking is also associated with testing the limits of the body, which is also included as a research subquestion in the thesis. In order to gain a more comprehensive view of the researched issue, not only the athletes themselves, but also the coach, sports doctor and physiotherapist were involved in the research. Qualitative methods were used during the research, which consisted of observations, interviews and document-based data.
Quality of patient's life with chronic pain
Čapková, Zuzana ; Vachková, Eva (advisor) ; Matulová, Jana (referee)
Author: Zuzana Čapková Institution: Department of Non-mediacal Studies, Faculty of Medicine in Hradec Králové, Charles University Title: Quality of patient's life with chronic pain Supervisor: Mgr. Eva Vachková, Ph.D. Number of pages: 121 Number of attachments: 8 Year of defense: 2023 Key words: pain, chronic pain, center of chronic pain, quality of life, WHOQOL-BREF The bachelor thesis deals with the quality of patient's life with chronic pain. In the theoretical part, I focused on the definition, physiology of pain, its division, diagnosis, pain assessment, therapeutic procedures in pain management, factors affecting pain, the role of the general nurse in the treatment of patients with chronic pain, pain management centres and a general description of the quality of life and the specific quality of life of patients with chronic pain. The empirical part presents the results of a quantitative investigation in the form of a non-standardized questionnaire that focused on questions related to chronic pain and a standardized WHOQOL-BREF questionnaire that assessed overall quality of life and health status. The research was conducted at the Regional Hospital Liberec, a.s. and at the Hospital Jablonec nad Nisou, p.o. Furthermore, the empirical part focused on comparing the quality of patient's life...

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