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3D Model of Cardial Tissue Electrical Propagation
Míková, Monika ; Mézl, Martin (referee) ; Hejč, Jakub (advisor)
The aim of this master thesis is to create a simple 3D electro-anatomical model of cardiac tissue that will be able to simulate the electrical activation in both a healthy heart and a heart with arrhytmogenic substrate. The model of electrical activation is realized in the COMSOL Multiphysics, simulation software for modelling using the finite element method. The Fitzhugh-Nagumo equation was used to model the excitatory feature of the myocardium and 2D models of myocardial tissue describing the propagation of action potential in healthy tissue, ischemic tissue, spontaneous action potential formation in the SA node, and spiral wave formation were first developed based on appropriate parameters. Subsequently, simplified 3D models of the heart describing the spread of excitement in a healthy heart, in the presence of accessory pathway and in third-degree atrioventricular block were created. The simplified 3D heart model offers a compromise between computational load and model complexity and can be used as a diagnostic tool for tissue and whole heart adjustment with appropriate equation parameter settings.
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ECG Generator in LabVIEW
Bayerová, Zuzana ; Tannenberg,, Milan (referee) ; Sekora, Jiří (advisor)
Bachelor thesis describes the principles of cardiac activity and deals with problems in the ECG signal. In an environment LabVIEW program was created a virtual instrument that generates the ECG signal. On the basis of familiarity with the methods for generating ECG signal method was used, using the similar sections of ECG curves with sinusoidal and triangular course. Virtual device allows you to change the heart rate and amplitude of waves and oscillations. It is possible to simulate a disturbances in the physiology of the heart. For example, different types of AV block, sinus, supraventricular and ventricular arrhythmias.
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3D Model of Cardial Tissue Electrical Propagation
Míková, Monika ; Mézl, Martin (referee) ; Hejč, Jakub (advisor)
The aim of this master thesis is to create a simple 3D electro-anatomical model of cardiac tissue that will be able to simulate the electrical activation in both a healthy heart and a heart with arrhytmogenic substrate. The model of electrical activation is realized in the COMSOL Multiphysics, simulation software for modelling using the finite element method. The Fitzhugh-Nagumo equation was used to model the excitatory feature of the myocardium and 2D models of myocardial tissue describing the propagation of action potential in healthy tissue, ischemic tissue, spontaneous action potential formation in the SA node, and spiral wave formation were first developed based on appropriate parameters. Subsequently, simplified 3D models of the heart describing the spread of excitement in a healthy heart, in the presence of accessory pathway and in third-degree atrioventricular block were created. The simplified 3D heart model offers a compromise between computational load and model complexity and can be used as a diagnostic tool for tissue and whole heart adjustment with appropriate equation parameter settings.
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ECG Generator in LabVIEW
Bayerová, Zuzana ; Tannenberg,, Milan (referee) ; Sekora, Jiří (advisor)
Bachelor thesis describes the principles of cardiac activity and deals with problems in the ECG signal. In an environment LabVIEW program was created a virtual instrument that generates the ECG signal. On the basis of familiarity with the methods for generating ECG signal method was used, using the similar sections of ECG curves with sinusoidal and triangular course. Virtual device allows you to change the heart rate and amplitude of waves and oscillations. It is possible to simulate a disturbances in the physiology of the heart. For example, different types of AV block, sinus, supraventricular and ventricular arrhythmias.
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