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Patient Perspective of Medication Information Desired
Kalaitzidis, Panagiotis ; Vlček, Jiří (advisor) ; Zimčíková, Eva (referee)
Title: Patient perspective of medication information desired Student: Kalaitzidis Panagiotis Tutor: Jiri Vlcek Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové Background: Even from the decade of 1970, patients wanted more information about drugs and did not want to be so depended on the information the physician provided them. Today patients are more than ever informed about their disease and the available and appropriate treatment, due to the high volume of information that can be acquired through the Internet. The traditional role of pharmacists was the provision of medicines to the population. However, nowadays, this role has been changed so as to include other tasks, such as management of prescribed medicines, and promotion of health, since pharmacists can serve as a source of expertise knowledge to the customers. Due to the fact that there is no relevant research for the case of Greek patients, this pilot research could help to fill this gap, by trying to find out what kind of information patients want to know about medicines in several pharmacies in Greece. Aim: The aim of this research is to examine what kind of information patients want related to medicines. More precisely, this research will try to identify the type of...
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Attitudes and beliefs on HPV infection and vaccination
Blašková, Dominika ; Zimčíková, Eva (advisor) ; Pokladníková, Jitka (referee)
ATTITUDES AND KNOWLEDGE OF HPV INFECTION AND VACCINATION Author: Dominika Blašková Supervisor: PharmDr. Eva Zimčíková, Ph.D. INTRODUCTION Human papillomavirus (HPV) is a DNA virus. The virus causes benign and malignant diseases of men and women such as laryngeal papillomatosis, genital warts, oropharyngeal carcinoma, cervical cancer, penile cancer and anus cancer. HPV can be prevented by appropriate precautionary measures. The main preventative method is vaccination against HPV. Besides vaccination, regular screening is necessary to detect premalignant changes on time. AIMS The aim of the theoretical part of the diploma thesis was to summarize the information about HPV, the diseases caused by human papillomavirus and vaccination against HPV, the main preventive measure. The primary aim of the practical part was to find out the level of HPV awareness among girls and boys and diseases caused by HPV. The secondary aim of the practical part was to find out opinions on HPV vaccination and determine the rate of vaccination against HPV among young people in Slovakia. METHODS The method of quantitative research taken in the form of a questionnaire was used in the diploma thesis. The survey was realized at two secondary schools in Svidník, Slovakia. The age range of respondents was 15-20 years. The data...
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ANTIBIOTIC CONSUMPTION ANALYSIS BASED ON HEALTH INSURANCE COMPANY DATA
Buriánková, Lenka ; Vlček, Jiří (advisor) ; Zimčíková, Eva (referee)
ANTIBIOTIC CONSUMPTION ANALYSIS BASED ON HEALTH INSURANCE COMPANY DATA Student: Buriankova L. Tutor: Vlcek J., Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Czech Republic Background: Overuse and misuse of antibiotics leads to increased resistance of microorganisms to antibiotics. There is a risk we will not have antibiotics effective against pathogenic microorganisms in future. It is therefore very important to make guidelines for rational prescribing and use of antibiotics. Aim: Analyze antibiotic consumption data package collected in given period depending on consumer age or sex. Analyze which group of doctor prescribes antibiotics in most cases. Analyze the most prescribed substances depending on different expression of consumption and compare obtained data with available data. Methods: Source of data is a database of employment insurance. The number of insurance clients was 129 699 in 2006 and 131 876 in 2007. Antibiotic use was evaluated, namely the group J01 of ATC system - Antibacterial drugs for systemic use. Data cover years 2006 and 2007. AISLP-CR, version 2008.4 is a database used for searching information about different drugs and substances. Obtained data were summarized in a database in Microsoft Excel. ATC / DDD system was...
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Adherence to treatment in patients after kidney transplantation
Vaňková, Barbora ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Adherence to Treatment in Patients after Kidney Transplantation Author: Barbora Vaňková Tutor: PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Kateřina Ládová, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Kidney transplantation (KT) is the best treatment option for patients with end- stage renal disease. However, despite its numerous benefits it requires a lifelong medical regimen of immunosuppressive treatment (IS) with a special emphasis on a strict medication adherence (MA). The objective of our study was to analyse MA in KT outpatients. We also intended to analyse non- adherence as one of the drug-related problems. Furthemore, we focused on analysis of the main self- management tasks. Methods: The prospective cross-sectional study was undertaken in one year period from March 2016 to March 2017 at the Haemodialysis Centre in the Teaching Hospital Hradec Králové. Patients ≥ 18 years old and at least 3 weeks after KT were addressed within their regularly scheduled visit to the nephrologist. Structured interview was performed by pharmacist to determine patients' self-reported MA to IS using validated Czech version of Medication Adherence Report Scale (MARS-CZ). In addition, patients were interviewed about other...
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Drugs and people III.
Hudcová, Petra ; Práznovcová, Lenka (advisor) ; Zimčíková, Eva (referee)
15. SUMMARY DRUGS AND PEOPLE III. Author: Hudcová Petra (Department of social and clinical pharmacy, Faculty of pharmacy in Hradec Králové, Charles university in Prague) Tutor: PharmDr. Práznovcová Lenka, Ph.D. (Department of social and clinical pharmacy, Faculty of pharmacy in Hradec Králové, Charles university in Prague) Backgroud: Availability of drugs is limited by many factors. Economic factors are one of the most important. The financial participation of patients on drugs is one of basic metod for regulation the costs in health. Increase the financial participation of patients on drugs and reduction stae costs on pharmacotherapy (in cases where it's possible in terms of availability) may be increased the availability of more expensive pharmacotherapy. Aim of study: The aim of the theoretical work is mapping the current situatian in the Czech republic in relation to the price of drugs. Practical part of the work is focused on the evaluation research conducted among pharmacy clients in pharmacy "Koruna" located in West Bohemian town Ostrov. Methods: The survey was conducted through questionnaire "People and drugs". This questionnaire was created on Department of social and clinical pharmacy, Faculty Of Pharmacy in Hradec Králové. Data was obtained from clients pharmacy in term of November - December...
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Analysis of drug-related problems in ward health care facility I.
Nováková, Kateřina ; Malý, Josef (advisor) ; Zimčíková, Eva (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate: Kateřina Nováková1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové Title of Thesis: Analysis of drug-related problems in ward health care facility I. Indroduction: Use of drugs in clinical practice is accompanied by the risk of occurence of drug-related problems. Drug-related problems can have negative influence on patients health and the economic side of the treatment. Therefore their monitoring and elimination are needed as well as indicating and efforts to preventing. Objective: The aims of this thesis were to revise medical records, identify and classify potential drug-related problems, describe management of selected drug-related problems. Methods: The revision was carried out from 10th to 13th December 2013 in rehabilitation institute in the Czech Republic. Complete medical records of randomly selected patients were used as a source of information. All data were recorded into database prepared for the needs of revision. The revealed drug-related problems were then replenished into the database and in the same time they were classified according to PCNE modified classification V5.1 and...
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Drugs and people III.
Podhrázská, Blanka ; Práznovcová, Lenka (advisor) ; Zimčíková, Eva (referee)
DRUGS AND PEOPLE III. Author: Podhrázská B., Department of social and clinical pharmacy, the Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech republic Leader: Práznovcová L., Department of social and clinical pharmacy, the Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech republic Introduction: Consumption of drugs is part of the pharmacoeconomics and makes it possible to measure the costs incurred by the state on illness and is an indicator of the necessity of drugs in any state. Aim of thesis: The Aim of thesis was to determine the consuption of the drugs in the Czech republic in the years 2004-2008 using available databases and questionnaires to avaluate how medicines are currently prescribed and used by patients. Method: 150 patiens were selected on random (98 women and 52 men, age 23 and over), who came to the pharmacy with prescription. Patients completed an anonymous questionnaire concerning personal data, prescription drugs, OTC drugs, regulatory fees and supplements. Results: The most of drugs are used in group C - cardiovascular system (43%), A - alimentary system and metabolism ( 11%), N - nervous system(11%) and M - musculosceletal system (10%). Patiens pay for OTC drugs monthly about 100 CZK (61% respondents). Deduction: Consumption of...
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Population and Drugs
Feberová, Beata ; Práznovcová, Lenka (advisor) ; Zimčíková, Eva (referee)
POPULATION AND DRUGS Autor: Feberová B., Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Czech Republic Tutor: Práznovcová L., Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Czech Republic Background: The cardiovascular prescription has significant role in fight cardiovascular disease, which they are head cause of death in most of industrial advanced countries. Aim of study: The objectiv of the diploma work was find out the cardiovascular prescription, analyse what kind effective matters included with medicinal preparation on the cardiovascular system was prescribe for patients in practice - which dosage and which combinations. Methods: The 150 patients (98 female, 52 male, age 21 and more years), who come in chemist with medical recipe was accidentally chosen. These patients complete list of questions pertain to drugs prescribed by doctor, drug published without prescription, drugs expended without medical recipe, footage behind drugs and medical care. Study was performed in period November - December 2007. Results: Drugs on the cardiovascular system (group C according to ATC classification) generated 48,5 % of the all analysis prescribed by doctor preparations. Mostly persons,...
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Application of explicite criteria of medications potentially inappropriate in the old age in the evaluation of quality of prescribing (III.)
Grešáková, Silvia ; Fialová, Daniela (advisor) ; Zimčíková, Eva (referee)
Introduction: Propotion of older people is rapidly increasing in the world population. Elderly represents a specific, heterogenous population which is because of many reasons more vulnerable to some adverse drug events. Many explicit criteria of potentially inappropriate medication used in the elderly have been developed in order to improve the quality and safety of geriatric pharmacotherapy. These criteria represent basic tools, defining fundamental prescribing rules for the evaluation of appropriate choice and dosing of medications in the old age and for the evaluation of potentially inappropriate prescriptions in older patiens. The aim of the diploma thesis was to compare advantages and disadvantages of explicit criteria published until the end of 2015 year and to summarizea list of allpotentially inappropriate medications in the elderly (regardless of diagnoses and concomitantly used medications), applicable in the epidemiological studies of the EU COST Action 1402project and in subsequent studies. Methods: Using systematic literature search in PubMed dataset, conducted in the period 04/2015 - 12/2015, all explicit and explicit- implicit criteria (published in the foreign peer- reviewed scientific journals bythe end of year 2015 and validated by expert panels) have been identified. Information...
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Pharmacovigilance: Drug regulation development and legislation overview.
Manišová, Michaela ; Kostřiba, Jan (advisor) ; Zimčíková, Eva (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate Mgr. Michaela Manišová Consultant PharmDr. Jan Kostřiba, Ph.D. Title of Thesis Pharmacovigilance: Drug regulation development and legislation overview. Introduction: Pharmacovigilance is a scientific discipline relating to the detection and evaluation of adverse drug reactions and other risks associated with the use of the medicinal products after marketing authorisation and implementation of the risk minimisation measures. Objectives: To analyze the legislation requirements in the area of pharmacovigilance for the medicinal products for human use in the European Union and their implementation in practice. Trends in adverse drug reactions reporting in the various pharmacovigilance systems (United States, Czech Republic, European Union), evaluation of the factors affecting reporting and the main benefits of spontaneous reporting. Methods: The legal requirements of the European Union, the Czech Republic and the United States was used as the source of information, followed by the official website of the Drug Regulatory Authorities, the best practices guidelines prepared by the European Medicines Agency and by the Food and Drug Administration, the harmonization guidelines issued by...
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