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The application of chlorine for public swimming pool water disinfection
Wagnerová, Andrea ; Svoboda, František (referee) ; Biela, Renata (advisor)
The bachelor thesis focuses on issues surrounding disinfectants of swimming pool water. The dissertation examines various chlorine based disinfectants as well as chlorine free disinfectants. Part of the thesis compares advantages and disadvantages of different possibilities of securing hygienic swimming pool water. Several complexes of public swimming pools in Brno and its neighbourhood were visited in order to examine the methods of disinfection, which are currently used at those swimming pools. Disinfectants based on chlorine are currently used the most for swimming pool water.
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Single nucleotide polymorphisms in the pathogenesis of mature B-cell neoplasms
Wagnerová, Andrea ; Szotáková, Barbora (advisor) ; Beránek, Martin (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Andrea Wagnerová Supervisor: prof. Ing. Barbora Szotáková, Ph.D., Mgr. Kateřina Černá Pilátová, Ph.D. Title of diploma thesis: Single nucleotide polymorphism in the patogenesis of mature B-cell neoplasms Chronic lymphocytic leukemia (CLL) is a disease characterized by clonal proliferation of B-lymphocytes. CLL is a lymphoproliferative disorder with a number of defined risk factors, but its etiopathogenesis remains unresolved to some degree. Over the past 10-15 years, there have been several studies that primarily suggest a genetic predisposition to the disease. The influence of external factors on the etiology of CLL has not been demonstrated. There is also a defined asymptomatic condition associated with CLL called monoclonal B-lymphocytosis, which is often referred to as a precursor of CLL. Immunophenotyping of lymphocytes by flow cytometry was performed in subjects of the control group (100 subjects) and the CLL/MBL group (patients diagnosed with CLL or MBL, 50 subjects). All subjects in the control and CLL/MBL groups were screened for selected genetic polymorphisms (rs17483466, rs735665, rs7176508, rs872071, rs13397985) that have been associated with the occurrence of CLL and MBL in other...
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Single nucleotide polymorphisms in the pathogenesis of mature B-cell neoplasms
Wagnerová, Andrea ; Szotáková, Barbora (advisor) ; Beránek, Martin (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Andrea Wagnerová Supervisor: prof. Ing. Barbora Szotáková, Ph.D., Mgr. Kateřina Černá Pilátová, Ph.D. Title of diploma thesis: Single nucleotide polymorphism in the patogenesis of mature B-cell neoplasms Chronic lymphocytic leukemia (CLL) is a disease characterized by clonal proliferation of B-lymphocytes. CLL is a lymphoproliferative disorder with a number of defined risk factors, but its etiopathogenesis remains unresolved to some degree. Over the past 10-15 years, there have been several studies that primarily suggest a genetic predisposition to the disease. The influence of external factors on the etiology of CLL has not been demonstrated. There is also a defined asymptomatic condition associated with CLL called monoclonal B-lymphocytosis, which is often referred to as a precursor of CLL. Immunophenotyping of lymphocytes by flow cytometry was performed in subjects of the control group (100 subjects) and the CLL/MBL group (patients diagnosed with CLL or MBL, 50 subjects). All subjects in the control and CLL/MBL groups were screened for selected genetic polymorphisms (rs17483466, rs735665, rs7176508, rs872071, rs13397985) that have been associated with the occurrence of CLL and MBL in other...
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Defects and shortcomings pool operations
Wagnerová, Andrea ; Lhotáková,, Zdeňka (referee) ; Biela, Renata (advisor)
The master thesis is focused on problems surrounding defects and deficiencies of running a swimming pool site. It deals with particular defects which can occur at swimming pool's site. Different public swimming pools in Brno were visited to conduct an evaluation of real defects and deficiencies. After conducting the overview of defects, a correction solution was design for each defect. The defects are ranked according a scale measuring danger which I created
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The application of chlorine for public swimming pool water disinfection
Wagnerová, Andrea ; Svoboda, František (referee) ; Biela, Renata (advisor)
The bachelor thesis focuses on issues surrounding disinfectants of swimming pool water. The dissertation examines various chlorine based disinfectants as well as chlorine free disinfectants. Part of the thesis compares advantages and disadvantages of different possibilities of securing hygienic swimming pool water. Several complexes of public swimming pools in Brno and its neighbourhood were visited in order to examine the methods of disinfection, which are currently used at those swimming pools. Disinfectants based on chlorine are currently used the most for swimming pool water.
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