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WATER+TOWN AQUADOMOS river story
Škapová, Veronika ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The architectural proposal is situated by the river Svratka nearby the city center of Brno. The proposed object turns its back to very busy street and opens to the river. It creates a city riverbank which is open to the public. The volume of the object reminds a wave. The object contains three main functions - exposition, information and research. The Exposition is based on the phenomenon of water. The Informations are placed in proposed auditorium, cafe and small gallery. The research is situated in laboratories and public study rooms.
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WATER+TOWN AQUADOMOS river story
Toman, Ondřej ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The result of design is architectural and urban design of unused area in Brno - Pisárky. This area was own by Water works company Brno. The area is situated next to the river Svratka. New research, information and exhibition center is designed on this place. The whole design was created in the context of river Svratka. The building which was designed there is called Aquadomos. This building consists of free pavilions. Each has a different use. The middle one contains main entrance, multipurpose recture halls, exhibitions areas, cash desk, information point and cafe. The largest pavilion contains exhibition area which is devided into six parts. The smallest pavilion which is situated close to the river contains administration department and laboratories. The external form, shape of building, is inspirated by river, waves, shape of landscape. Park is designed in the rest of parcel. In the park there are terraces to the river for easy access closer to the river Svratka. One of the main idea was to bring life closer to the river, to rediscover river in the structure of Brno.
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WATER+TOWN AQUADOMOS river story
Smirnov, Anton ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The proposal is to create an architecturally interesting and unique, comprehensive, research-modern complex information and visitor center "WATER TOWN AQUADOMOS". The project addresses the urban design concept of the complex and its individual elements - visitor center with aquariums, museums and galleries with the history of the river Svratka outdoor recreation area with a water surface, the input element and an underground car park for visitors. The design of all elements are reflected themes of inspiration vody.Navržený house responds to the urban context in the area and complements the present block of buildings on the waterfront. The main entrance is placed on the most exposed part of the plot, the entrance to the underground garage and restaurant supply is oriented to the street Pisárecká, near křižovatky.Budova is fashioned in the shape of two prisms, which are linked through a central part. The shape of the building is influenced by communication and development plan.
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The use of CAM assay for characterization and study of cancer cell invasive properties
Vágnerová, Lenka ; Dvořák, Michal (advisor) ; Geryk, Josef (referee)
The chorioallantoic membrane (CAM) of chicken embryos belongs to the in vivo model systems frequently used for the study of angiogenesis and cell invasiveness. Using CAM assay we have tested selected chicken sarcoma cell lines characterized by different angiogenic properties and different ability to form metastasis. In addition to CAM assay, several other methods have been used to characterize the phenotype of these cell lines. We have selected a few proteins which could significantly influence the angiogenic and metastatic properties of investigated cell lines. We have established cell lines stably overexpressing these genes and compared their phenotypes with parental cell lines. We have shown that genes encoding ISL1, ARNT2, PROM1, HOXA11 proteins participate, in our experimental model, in activation of programes controlling angiogenesis and cell invasion.
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The use of CAM assay for characterization and study of cancer cell invasive properties
Vágnerová, Lenka ; Dvořák, Michal (advisor) ; Geryk, Josef (referee)
The chorioallantoic membrane (CAM) of chicken embryos belongs to the in vivo model systems frequently used for the study of angiogenesis and cell invasiveness. Using CAM assay we have tested selected chicken sarcoma cell lines characterized by different angiogenic properties and different ability to form metastasis. In addition to CAM assay, several other methods have been used to characterize the phenotype of these cell lines. We have selected a few proteins which could significantly influence the angiogenic and metastatic properties of investigated cell lines. We have established cell lines stably overexpressing these genes and compared their phenotypes with parental cell lines. We have shown that genes encoding ISL1, ARNT2, PROM1, HOXA11 proteins participate, in our experimental model, in activation of programes controlling angiogenesis and cell invasion.
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WATER+TOWN AQUADOMOS river story
Toman, Ondřej ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The result of design is architectural and urban design of unused area in Brno - Pisárky. This area was own by Water works company Brno. The area is situated next to the river Svratka. New research, information and exhibition center is designed on this place. The whole design was created in the context of river Svratka. The building which was designed there is called Aquadomos. This building consists of free pavilions. Each has a different use. The middle one contains main entrance, multipurpose recture halls, exhibitions areas, cash desk, information point and cafe. The largest pavilion contains exhibition area which is devided into six parts. The smallest pavilion which is situated close to the river contains administration department and laboratories. The external form, shape of building, is inspirated by river, waves, shape of landscape. Park is designed in the rest of parcel. In the park there are terraces to the river for easy access closer to the river Svratka. One of the main idea was to bring life closer to the river, to rediscover river in the structure of Brno.
|
|
|
WATER+TOWN AQUADOMOS river story
Smirnov, Anton ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The proposal is to create an architecturally interesting and unique, comprehensive, research-modern complex information and visitor center "WATER TOWN AQUADOMOS". The project addresses the urban design concept of the complex and its individual elements - visitor center with aquariums, museums and galleries with the history of the river Svratka outdoor recreation area with a water surface, the input element and an underground car park for visitors. The design of all elements are reflected themes of inspiration vody.Navržený house responds to the urban context in the area and complements the present block of buildings on the waterfront. The main entrance is placed on the most exposed part of the plot, the entrance to the underground garage and restaurant supply is oriented to the street Pisárecká, near křižovatky.Budova is fashioned in the shape of two prisms, which are linked through a central part. The shape of the building is influenced by communication and development plan.
|
|
|
WATER+TOWN AQUADOMOS river story
Škapová, Veronika ; Vágnerová, Lenka (referee) ; Poslušná, Iva (advisor)
The architectural proposal is situated by the river Svratka nearby the city center of Brno. The proposed object turns its back to very busy street and opens to the river. It creates a city riverbank which is open to the public. The volume of the object reminds a wave. The object contains three main functions - exposition, information and research. The Exposition is based on the phenomenon of water. The Informations are placed in proposed auditorium, cafe and small gallery. The research is situated in laboratories and public study rooms.
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