National Repository of Grey Literature 8 records found  Search took 0.01 seconds. 
Neurosonological markers of cognitive decline progression in patients with dementia
Soukupová Urbanová, Barbora ; Hort, Jakub (advisor) ; Školoudík, David (referee) ; Horáček, Jiří (referee)
Alzheimer's disease represents an important socio-economic problem worldwide. Its complex and not entirely clear pathophysiological mechanisms are subject of intensive research with the aim to identify the affected individuals very soon in the disease process and to find efficacious prevention or treatment. According to recent knowledge, a multifactorial microangiopathy plays a role in the disease development. Probably both traditional vascular risk factors as well as mechanisms linked to neurodegeneration with amyloid accumulation are the factors involved. This work presents a summary of up to date knowledge about Alzheimer's disease vascular risk factors, signs of vascular impairment on brain imaging and possible interactions of vascular and neurodegenerative pathophysiological pathways. It focuses on the neurosonological signs of brain vascular impairment and presents own outcomes in this research area. Using cross-sectional and longitudinal design, the study demonstrates functional impairment of brain microcirculation in patients with various cerebrovascular burdens and various degrees of cognitive decline and it identifies the most appropriate neurosonological parameter in the prediction of cognitive decline progression. On the same study sample it explores the association of other vascular...
Neurosonological markers of cognitive decline progression in patients with dementia
Soukupová Urbanová, Barbora ; Hort, Jakub (advisor) ; Školoudík, David (referee) ; Horáček, Jiří (referee)
Alzheimer's disease represents an important socio-economic problem worldwide. Its complex and not entirely clear pathophysiological mechanisms are subject of intensive research with the aim to identify the affected individuals very soon in the disease process and to find efficacious prevention or treatment. According to recent knowledge, a multifactorial microangiopathy plays a role in the disease development. Probably both traditional vascular risk factors as well as mechanisms linked to neurodegeneration with amyloid accumulation are the factors involved. This work presents a summary of up to date knowledge about Alzheimer's disease vascular risk factors, signs of vascular impairment on brain imaging and possible interactions of vascular and neurodegenerative pathophysiological pathways. It focuses on the neurosonological signs of brain vascular impairment and presents own outcomes in this research area. Using cross-sectional and longitudinal design, the study demonstrates functional impairment of brain microcirculation in patients with various cerebrovascular burdens and various degrees of cognitive decline and it identifies the most appropriate neurosonological parameter in the prediction of cognitive decline progression. On the same study sample it explores the association of other vascular...
Optimization of Tax Burden of Legal Entity
Urbanová, Barbora ; Ing. Daniel Orel, Ph.D (referee) ; Svirák, Pavel (advisor)
Bachelor thesis deals with advantages and disadvantages of diferent ways of funding a vehicle for company MAVI ÚČTO s.r.o.. Loans and leases were requested for the analysis from three company. They are examined from the point of view of the advantage, the amount of the overpayment and their impact on the amount of the tax base in each period. Based on the comparison of the individual variants and the conditions set by the company, the most optimal financing option is selected.
The civil elites at the local level
Urbanová, Barbora ; Müller, Karel (advisor) ; Kný, Daniel (referee)
The thesis examines the process of recruiting new political elites, which is considered as an essential prerequisite for the restoration of a democratic society in the Czech Republic. The work examines the civic society and its involvement in the political life and activities on the municipal political level. The case study concerns the village of Dolní Břežany where the significant processes have taken place since the year 2002 in order to strengthen the transparency of politics. A questionnaire was distributed in Dolní Břežany where the questions dealt with the citizens´ life satisfaction in the village, their participation in public life and it investigated whether their involvement is or is not connected with an interest in politics or it is just connected with the existence of problems and their solution. Furthermore, the interviews with the executive representatives (between the years 2002 and 2014) gather their views on politics, the public and political participation in general. The aim was to find out what inspired the new political elites to enter the politics and stay politically active for such a long time. The work confirms a hypothesis that a goal of the new political representatives, who were elected in Dolní Břežany in 2002, was to improve their life conditions in the village. The elites remained politically active due to their clear conception of the future village development. The citizens´ confidence in political leaders and a high satisfaction with the community life increased also their interest in politics and public affairs.
The Importance of Elections and Electoral System Formation during the Change of Regime in Central European countries
Urbanová, Barbora ; Němec, Jan (advisor) ; Kuta, Martin (referee)
The bachelor thesis deals with processes of transition to a democracy and related formation of electoral systems during or after the collapse of authoritarian regimes in Czechoslovakia, Hungary and Poland. The aim is to analyze events connected with the collapse of regime and to explain the influence and the importance of electoral system selection, which helped with the creating and preservation of democracy in these countries. The first chapter deals with electoral systems. The second chapter analyzes processes of transition to democracy. The third chapter deals with specific case studies on individual countries compared. From the point of view of the new democratic regime establishment, each of the country in question went through the different mode of transition to a democracy. In each country the role of elites was different -- their importance was emphasized in Hungary, on the other hand the elite of the previous regime in Czechoslovakia were suppressed thanks to the social support to a new democratic opposition. In Poland they tried to find the calm solution of the situation, they wanted as much power as possible (which they were deprived of by the opposition very quickly).The electoral systems for the support of transition process to democracy were also different, the transformation however was without bigger problems in each of the three countries. The importance of electoral processes related especially to the restoration and revival of party system, which proved to be a basic stone of political system in the democratic countries.

See also: similar author names
2 Urbanová, Babeta
3 Urbanová, Berenika
1 Urbanová, Beáta
1 Urbanová, Blanka
1 Urbanová, Bohumila
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