|
|
2D numerical modelling of shallow water flow in floodplains
Monhartová, Pavlína ; Sýkora, Lukáš (referee) ; Dráb, Aleš (advisor)
The aim of the thesis is hydraulic computation of shallow water flow in floodplains with using 2D numerical modelling. Processing river is Dyje in the south of Moravia in location Břeclav. For model creation is necessary to know the software, accumulate input data and prepare model input parameters. Output data are process to form of maps water depths and maps water flow velocities.
|
|
|
Pyridine sulphides as antituberculotic active compounds
Sýkora, Lukáš ; Klimešová, Věra (advisor) ; Kuneš, Jiří (referee)
This diploma thesis is devoted to antituberculosis drugs research. A very briefly depicts of genus Mycobacterium, structure and composition of mycobacterial cell wall allowed here better process and determination of mechanisms of antituberculosis drugs targets. The synthesis selected derivates of pyridine sulfides: 4- (phenethylsulfanyl)pyridine-2-carbonitriles are the main aim of the diploma thesis. As well as a possible mechanism of action these substances is discussed. Thus a series of 4-(phenethylsulfanyl)pyridine-2-carbonitriles were synthesized. The structures were confirmed by IR spectra, NMR spectra and elementary analyses. Antimycobacterial activities these compounds were tested against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium kansasii. None of prepared substances exhibited activity (against M. tuberculosis) comparable to clinical used antituberculosis drugs. Significant activity was observed (in compare with isoniazide) against M. kansasii and M. avium.
|
|
|
Pojištění odpovědnosti za škodu způsobenou provozem vozidel MHD
Sýkora, Lukáš
The bachelor thesis deals with the development of insurance from the first signs of insurance to the present. It also explains all the important terms related to this issue. Further focuses are primarily on non-life insurance, consequently to the area of motor third party liability insurence. It offers a view of the history of Brno public transport. It describes the current situation and looks into the future visions. Last but not least, it points to risk areas and areas with the highest traffic accident rates in Brno.
|
|
|
Pyridine sulphides as antituberculotic active compounds
Sýkora, Lukáš ; Kuneš, Jiří (referee) ; Klimešová, Věra (advisor)
This diploma thesis is devoted to antituberculosis drugs research. A very briefly depicts of genus Mycobacterium, structure and composition of mycobacterial cell wall allowed here better process and determination of mechanisms of antituberculosis drugs targets. The synthesis selected derivates of pyridine sulfides: 4- (phenethylsulfanyl)pyridine-2-carbonitriles are the main aim of the diploma thesis. As well as a possible mechanism of action these substances is discussed. Thus a series of 4-(phenethylsulfanyl)pyridine-2-carbonitriles were synthesized. The structures were confirmed by IR spectra, NMR spectra and elementary analyses. Antimycobacterial activities these compounds were tested against Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium kansasii. None of prepared substances exhibited activity (against M. tuberculosis) comparable to clinical used antituberculosis drugs. Significant activity was observed (in compare with isoniazide) against M. kansasii and M. avium.
|
|
|
2D numerical modelling of shallow water flow in floodplains
Monhartová, Pavlína ; Sýkora, Lukáš (referee) ; Dráb, Aleš (advisor)
The aim of the thesis is hydraulic computation of shallow water flow in floodplains with using 2D numerical modelling. Processing river is Dyje in the south of Moravia in location Břeclav. For model creation is necessary to know the software, accumulate input data and prepare model input parameters. Output data are process to form of maps water depths and maps water flow velocities.
|
|
|
Interactive Visualisation of RELAX NG Schemas
Sýkora, Lukáš ; Kosek, Jiří (advisor) ; Ralbovský, Martin (referee)
The aim of this thesis is to create a tool for visualisation of RELAX NG schemas. RELAX NG schemas define a form of XML documents. They determine what elements and attributes can be used in the document and how they can be combined. Visualisation of schemas enables easier orientation in the structure of RELAX NG patterns. This can be useful for both developers of schemas and users who use schemas for creation of XML documents. RELAX NG schema can be written using XML, which enables its visual representation by means of tree structure. Moreover, the model of the tree is interactive which enables users to display only the branches they are interested in. The aim will be reached in several steps. At first, it is necessary to analyze properly the structures of RELAX NG language with respect to their future visualisation. Next step is SVG format for description of vector graphics. SVG format can be written using XML as well. Interactivity of the model described by SVG is enabled by ECMAScript. The conversion from RELAX NG to SVG graphics will be done by means of XSLT transformation. The main contribution of this thesis will be the visualisation which facilitates the orientation in the schema for both users and developers. Only XSLT processor and a file with XSLT transformation will be needed for the visualisation of RELAX NG. The file with XSLT transformation will be the output of this thesis. The thesis is divided into three main parts. The first part is focused on the analysis of the structures of RELAX NG language and the possibilities of their visualisation. Particular attention will be given to the current possibilities of graphic interpretation of schemas. The second part is devoted to the design of graphic symbols for individual nodes of the graphic model and the possibilities of their interaction. The third part deals with the prototype implementation of transformation of RELAX NG to SVG graphics.
|
guest ::
RSS feed.