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Synthesis of New Seleninic Acid Compounds as Potential Antileishmanial Agents
Pechová, Marcela ; Pour, Milan (advisor) ; Roh, Jaroslav (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Student: Marcela Pechová Supervisor: Prof. RNDr. Milan Pour, Ph.D. Title of Diploma Thesis: Synthesis of New Seleninic Acid Compounds as Potential Antileishmanial Agents Selenium containing organic compounds possess promising in vitro antiparasitic activity against Leishmania infection. Various selenocyanate and diselenide derivatives with different functional groups in the aryl ring and in the aliphatic chain, displaying promising leishmanicidal activity and higher selectivity indexes than those obtained for the reference drugs, miltefosine and edelfosine, have recently been synthesized. Within this thesis, the synthesis of new seleninic acid derivatives from selenocyanates and diselenides is described. Four new seleninic acids have been prepared.
Rozlišovací schopnost barev na pomezí fotopického/mezopického vidění
Vik, Michal ; Viková, Martina ; Pechová, Marcela
The human eye is most sensitive to the wavelength region 555 nm, with decreasing light intensity is shifted the sensitivity of the human eye to shorter wavelengths. Subjective evaluation of observers (Farnsworth-Munsell 100 Hue test and a set of color chips) were performed under seven luminous levels on mesopic and photopic luminance level, which have been achieved application of proof car foils with different luminous transmission on polymethylmethacrylate plates. A select group of observers was divided according to FM 100 Hue Test to the categories superior (The total overall error score to 19) and average (The total overall error score to 100) by the total overall error score. For the evaluation of the observers was chosen set of color samples defined by National Coil Coaters Association (A prismatic display of Measured color difference). They are colorful papers square chips with the measured color difference with 1 or 5 units (progressively according the axis L + a + b +, L-, a-, b-) from the center chip (16 center chip, total of 96 samples). Of the evaluated data it was found that the evaluation of color differences on chips with small color difference (DE = 1) is the distinction these chips possible even at 1 lux. From this luminous lighting increased differentiation between trials observers. For chips with a larger color difference (DE = 5) were the differences in evaluation observers at all high luminance levels.

See also: similar author names
2 PECHOVÁ, Magdaléna
14 PECHOVÁ, Martina
6 PECHOVÁ, Michaela
2 Pechová, Magdaléna
1 Pechová, Marika
2 Pechová, Markéta
14 Pechová, Martina
6 Pechová, Michaela
1 Pechová, Miroslava
2 Pechová, Monika
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