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Pedagogical principles in youth work in the Church of the Christian fellowship
NOVÁK, David
The thesis deals with pedagogical principles applicable in youth work in the Church of the Christian fellowship. The first part characterizes the Church of the Christian fellowship and its specifics in youth work. Next it describes very pedagogical principles, in fundamental and then in specific way of leisure education. The third part describes pedagogical principles that are applicable in youth work in the Church of the Christian fellowship.
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Methodology of processing and archiving of aerial survey data in archaeology
Gojda, Martin ; Novák, David ; Kuna, Martin ; Vavřín, P. ; Bíšková, J.
The Methodology of Processing and Archiving of Aerial Survey Data in Archaeology is one of the outputs that concludes not only the research project Archaeology from the Sky, but also one of the stages of aerial archaeology and digitization of archaeological data in the Czech Republic. Both of these areas began to develop in the Czech Republic in the early 1990s, initially independently, and over time in ever closer cooperation. These two branches of archaeological work in the Czech Republic have undergone a deeper transformation in the past decade, which has meant the creation of an institutionalised research infrastructure, the Archaeological Information System of the Czech Republic, for the field of digital documentation, and a full-fledged move towards digital technologies for data collection, preservation, analysis and presentation for aerial archaeology. Nowadays it is hard to imagine aerial survey without digital technologies and at the same time the image of the country's archaeological heritage without attractive and professionally valuable aerial images. Having learnt from the natural disasters at the Archaeological Institutes of the CAS in 2002 and 2008, we now know that digitisation is the only way to save older data, to secure them from future loss and to make them fully usable (by making them accessible to a wide range of experts and other interested parties). Leaving aside the development of proprietary technologies, which will always be a task for a narrower circle of specialists, the development of digitisation in aerial archaeology brings two main challenges for most archaeologists working in this field. The first is the conversion and description of legacy, analogue documents into digital form, as old images can contain irreplaceable information that it would be a shame to leave buried in archives and exposed to the gradual loss of their informational value. The second challenge is to recognise the demands that the advent of the information society in general brings with it, i.e. the need for greater cooperation between professionals, sharing of information and coordination of professional practices. While the entire Archaeology from the Sky project focused on the first task, this methodology offers help with the second task. Methodologies of this type are now being developed throughout Europe, but they are not yet numerous and by no means cover all areas of archaeological work. Only a methodology (“Guide to Good Practice”) prepared in 1999 by the leading British institution Archaeology Data Service has been published directly on our topic, however, it is already evident from the date of its publication that it cannot fully cover the needs of today, not to mention the specific situation of Czech archaeology and its procedures. The European Archaeological Council's 2014 manual, which was also published in Czech translation, focuses on the archiving of archaeological data, but it is general and does not address the specific issues of aerial archaeology. Of the Czech manuals, only the 2017 Methodology for the Identification of Immovable Archaeological Monuments touches our topic in a marginal way. The authors of the presented manual and the members of the expert team of the Archaeology from the Sky project are convinced that this methodology will contribute to the protection of a specific part of the archaeological heritage in the Czech Republic. We also believe that thousands of aerial archaeological images, which are already available through the AMCR Digital Archive, will soon be joined by other collections, and that this fact will contribute to the development of professional research and public interest in archaeology.
Plný tet:  PDF
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Vibration energy harvester as a tuned mass damper
Novák, David ; Machů, Zdeněk (referee) ; Rubeš, Ondřej (advisor)
This bachelor thesis it's about vibration energy harvester as a tuned mass damper the design of a vibration generator as a dynamic vibration damper.The work contains a research part, which examines the methods of damping mechanical systems and the influence of the vibrating generator on the vibrating base. Based on this knowledge, equations of motion were derived for the design of the model in the SIMULINK program, where we optimized the parameters for maximizing the obtained electrical power and maximizing the damping effect.
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Legal consequences with respect to the breach of contract under civil law
Novák, David ; Švestka, Jiří (advisor) ; Salač, Josef (referee)
S u m m a r y The goal of this thesis is to analyse the legal consequences of the breach of contract, especially under civil law, although, some essential comparison with legal regulation of commercial law is given, too. The text is divided into ten chapters. In the introduction, i. e. in the first two chapters the term of contract is defined and then the basic legal principles of the contractual law are enumerated and described in respect of the topic. The third chapter deals with the subject of the paper globally and shortly characterises each consequence of the breach of contract. The account of them is also given. The following chapters provide complete information how every consequence works and which part it plays in the Czech legal system. Specifically, Chapter Four is focused on debtor's delay and Chapter Five on creditor's delay. Chapter Six investigates liability for damage and damages a bit, as well. Chapter Seven deals with liability for defects and Chapter Eight is about contractual fine. In Chapter Nine is mentioned discharge of contract and its consequences. Each of in this paragraph enumerated chapters describes its subject itself and also relevant related problems in context with practice of the courts. In the last chapter, i. e. in the Conclusion is the whole topic shortly summarized with...
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Human lymphopoiesis and its examination via single-cell analysis
Novák, David ; Kalina, Tomáš (advisor) ; Drbal, Karel (referee)
Development of human B-lymphocytes is a convoluted process. A self-renewing stem cell progenitor in a primary lymphoid tissue commits to the lymphoid lineage. Subsequent B-lineage commitment entails somatic gene recombination processes which lead to the eventual expression of a surface antigen receptor. Functionality of the B-cell receptor, as well as successful testing for autoreactivity by the cell, are preconditions for the differenti- ation of a mature B-lymphocyte. Processes within this development are often investigated using single-cell analysis via flow cytometry, fluorescence-activated cell sorting and mass cytometry. Coupling these high-throughput methods with modern approaches to data analysis carries enormous potential in revealing rare cell populations and aberrant events in haematopoiesis. Keywords: B-lymphocyte, lymphopoiesis, flow cytometry, FACS, mass cytometry, clus- ter analysis, FlowSOM, PCA, t-SNE, Wanderlust.
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Drop coating deposition Raman microspectroscopy (DCDR) of carbohydrates
Novák, David ; Kopecký, Vladimír (advisor) ; Kočišová, Eva (referee)
The work is focused on the usage of drop-coating Raman (DCDR) spectroscopy in the study of carbohydrates. DCDR spectroscopy offers a lowering of the detection limits by the coffee-ring effect and minimization of the water signal while keeping similarity to the spectrum obtained from the solution. The similarity is achieved due to the glassy phase, in which molecules have a random orientation and probably retain the first solvation envelope. However, for small molecules, the situation is complicated by both the low efficiency of the coffee-ring effect and the tendency to crystallize. In this work, we studied glucose, galactose, lactose, maltose, trehalose and cyclodextrin to cover the basic structural diversity of sugars - from monosaccharides, disaccharides to oligosaccharides. It was successfully found the concentration range for DCDR spectroscopy of mono and disaccharides (ca. 1-30 mM), while maintaining the glassy phase of the deposit, and to point out the complications associated with the crystallization of polysaccharides. We compared the obtained DCDR spectra with the spectra of polycrystalline samples, from which they clearly differed. Subsequently, we measured the concentration dependences, up to saturated solutions, whose Raman spectra were analysed by factor analysis to capture the...
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Studying lymphocyte development using mass cytometry
Novák, David ; Stuchlý, Jan (advisor) ; Špidlen, Josef (referee)
Studying lymphocyte development using mass cytometry Abstract Development of mature lymphocytes, a white blood cell subtype, is crucial for the correct function of the human immune system. Currently, developmental pathways of lymphocytes can be studied using high-throughput single-cell measurements. In particular, mass cytometry enables the study of immunologically relevant pheno- typic and functional markers on a vast scale. In this work I present my individual contribution to tviblindi, a powerful software tool for analysis of cytometric data aimed at uncovering developmental trajectories. tviblindi is a package written in R, Python and C++. It provides a means to integrate prior knowledge with data analyses grounded in graph theory and algebraic topology. tviblindi is accessible to biological researchers without background in computer science or mathematics. It is an addition to the expanding field of trajectory inference in single-cell data. Furthermore, I review current knowledge of T-cell development and conduct a tviblindi analysis thereof using human thymus and peripheral blood datasets and evaluate the results. 1
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Studying lymphocyte development using mass cytometry
Novák, David ; Stuchlý, Jan (advisor) ; Špidlen, Josef (referee)
Studying lymphocyte development using mass cytometry Abstract Development of mature lymphocytes, a white blood cell subtype, is crucial for the correct function of the human immune system. Currently, developmental pathways of lymphocytes can be studied using high-throughput single-cell measurements. In particular, mass cytometry enables the study of immunologically relevant pheno- typic and functional markers on a vast scale. In this work I present my individual contribution to tviblindi, a powerful software tool for analysis of cytometric data aimed at uncovering developmental trajectories. tviblindi is a package written in R, Python and C++. It provides a means to integrate prior knowledge with data analyses grounded in graph theory and algebraic topology. tviblindi is accessible to biological researchers without background in computer science or mathematics. It is an addition to the expanding field of trajectory inference in single-cell data. Furthermore, I review current knowledge of T-cell development and conduct a tviblindi analysis thereof using human thymus and peripheral blood datasets and evaluate the results. 1
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