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Sewerage and WWTP Křelov, Břuchotín-building technology project
Novák, Jan ; Štěrba, Martin (referee) ; Henková, Svatava (advisor)
The subject of my work is to lower construction site waste water treatment plant Křelov - Břuchotín. In more detail, I focused mainly on the implementation of the circular tanks sewage treatment plant. These tanks prescription processing technology formwork and concreting circular tanks. It also contains a technical report, technical report building equipment, a study of the main technological stages of the building, site, design of mechanical assembly, inspection and test plan solved the technological regulation and scheduling.
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Small hydropower plant
Novák, Jan ; Pavlů, Jaroslav (referee) ; Fiedler, Jan (advisor)
The basic aim of the Bachelor Thesis is the detailed description of the development and the currect state of hydraulic power plants in the Czech Republic. Moreover, there are mentioned other possibilities of the usage and suitable localities for the build-up or renewal. Furthermore, the work deals with a small hydraulic power plant in Letohrad. It describes hydrological conditions and the design of the existing hydro-electric plant. The thesis continues with the computational part which compares two versions of the mechanical and the technological solution. The first version takes into account the instalation of one turbine and the second one focuses on the placement of three turbines with the same parameters. After the interpretation it has been found that the hydroenergetical potential of flow is more efficient in the first alternative. In the conclusion, there are revenue calculations for produced energy and the recovery of investment.
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The Standards of Transformer and Switching Station Operating Staff Training.
Nerušil, Ondřej ; Novák, Jan (referee) ; Toman, Petr (advisor)
While gathering the in-field experience to improve my professional grade I was introduced to the Chief of the Maintenance centre of Semperflex Optimit company Ltd. Thanks to that I have become familiar with the company‘s production‘s strategy, subdivisions of the operative maintenance centre as well as with the running of the part of electro-maintenance unit focusing the HV specialists. Simultaneously with my visit in the company I have been thinking over the subject of my bachelor´s thesis. Especially what took my interest was the HV branch of the electro-maintanance centre. What kind of qualifacation is necessary? How to achieve it? And what are the conditions for working with the HV unit? Is there any system of keeping the sufficient knowledge, work habits and skills? These, all together with other questions I have asked myself, convinced me to give my bachelor´s thesis the title „ The standards of the switchroom and transformer station’s worker maintenance.“
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Junction on Motorway R52 near Moravany
Lička, Vojtěch ; Novák, Jan (referee) ; Holcner, Petr (advisor)
My diploma thesis deals with a connection of Videňská street to the future residential district situated between Přízřenice and Modřice. The level of this thesis is a technical study. The main topic of the thesis is a design of an interchange on the Vídeňská and Moravanská streets. The thesis is focused on a technical verification of variable ramps’ connections from Vídeňská street to Moravanská street. Another important point of the thesis is an improvement of security quality of cycle traffic and a creation of a traffic junction of the city transportation system in this area. The SWOT analysis was applied to evaluation and selection the most advantageous variant of the variants. Depending on SWOT analysis, the thesis is focused on more detailed design of the most advantageous variant.
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Residential house Jihlava-technological phase of construction site
Novák, Jan ; Mesiarkin, Jan (referee) ; Henková, Svatava (advisor)
The subject of my bachelor´s thesis is to implement the rough upper construction of residential house in Jihlava. Processing Technology in detail the rules for building and assembly of prefabricated panels SPIROLL. It also contains a technical report, technical report building equipment, building equipment, mechanical assembly design, safety and environmental protection, inspection and test plan, schedule, itemized budget and the export ceiling panels SPIROLL.
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Chování spotřebitelů na trhu s alkoholickými nápoji
Novák, Jan
The diploma thesis is focused on consumer behaviour on the market for al-coholic beverages in the Czech Republic. The goal is to identify the key factors that influence consumers to consume alcohol. Using secondary data, the market for alco-holic beverages was analyzed with a focus on average alcohol consumption and in-dividual types of alcoholic beverages. At the same time, a questionnaire survey of respondents was added, and the results of the work revealed differences in the rea-sons that lead to the consumption of alcoholic beverages, including the influence of cultural, family and economic factors. The actual work includes the segmentation of respondents using cluster analysis and their division into five clusters according to differences in consumption behaviour, at the same time it is supplemented with rec-ommendations aimed at reducing alcohol consumption in the Czech Republic.
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Natural restoration of mining sites: Vegetation succession and soil development: A case study from granodiorite quarries and dumps near the town Skuteč
Chuman, Tomáš ; Šefrna, Luděk (advisor) ; Novák, Jan (referee) ; Hradecký, Jan (referee)
Ir !ntroduction Environmenta| impaď caused by mining is considerab|e' The impact of mining on re|ief and landscape character is particularly substantial as could be documented on earth material transfer. While transfer of earth material caused by natural processes (erosion, sedimentation) is about 4 millions of cubic meters per year, anthropogenic transfer is close to 330 millions (Kukal' 2006) and material transfer due to mining represents the greatest proportion' lt is estimated that the surface minera| extraďion already covers 1% of the |and surface (Wa|ker & del Moral 2003). |n the czech Republic the extent of mining sites reached 0,8% in 2006 (Statistical Environmental Yearbook of the Czech Republic 2008). Miningcausesineversib|emodificationofre|ieíremovesvegetationandsoi|cover causing loss of biotopes. on the other hand mining creates new sites in the landscape e'g' water bodies, rock walls and screes. These sites are often unique and contrasting with the surrounding landscape and might harbor specific species afrer mine/quarry abandonment. Traditional approach to restoration was considered to be the restoration (reclamation) of production, whether agricultural or forestry, causing elimination of potential site diversity by morphology adjustment' topsoil application and tree planting or trefoil-grass...
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Adipose etrogenisation and other anthropological aspects of obesity
Novák, Jan ; Sedlak, Petr (advisor) ; Bezdíček, Ondřej (referee) ; Bendlová, Běla (referee)
This work presents an anthropological view of obesity. It introduces the concept of adipose estrogenization and describes its relationship to pelvic morphology. Further, secular changes in the prevalence of latent obesity, the consequences, and the etiology of this condition are described. The work also validates tools for assessing chronotype, subsequently associating these metrics with sociodemographic factors, including obesity. The key part of this project present study focused on changes in the morphology of the bony pelvis in the context of pubertal history of obesity. It is a longitudinal study (n = 238) with an anthropometric examination after 8 years and an estimation of sex hormones. The main observation was that adult men with a history of obesity had more gynoid (relatively wider) pelvic bone morphology and altered levels of sex hormones, i.e., reduced testosterone levels and an increased relative proportion of estradiol to testosterone, i.e., estrogenization. This was manifested with habitual pelvic feminization, which serves as a marker of estrogenization and a retrospective marker of obesity. In the context of this study, a Letter to the Editor is added as a correction to the publication, interpreting these findings as a possible explanation for the shorter second stage of labor in...
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Physiology and Pathology of unconventional lymphocytes
Zubatá, Ivana ; Novák, Jan (advisor) ; Szotkowski, Tomáš (referee) ; Vydra, Jan (referee)
MAIT cells, mucosal-associated T lymphocytes, are a group of immune cells that have both innate and adaptive immunity abilities. They are defined by the expression of a semi-invariant TCR chain. They exhibit anti-infective potential with cytotoxic effector functions and immunomodulatory capabilities. The primary activation pathway is through the MR1 molecule of the non-classical MHC Ib class which is exerted in defense against bacteria and mycoses. MAIT cells are also able to TCR-independent activation by proinflammatory cytokines. They are involved in cytokine storms mediated by bacterial superantigens and in antiviral defense. They respond rapidly by producing a wide range of inflammatory mediators, including the repertoire of adaptive immunity Th1, Th2 and Th17 lymphocytes. Recent work shows resistance to some xenobiotics. This dissertation presents the results of an investigation of the phenotype of MAIT cell subpopulations measured by flow cytometry. By stimulation with ionomycin and PMA we analyzed their repertoire of cytotoxic abilities. In the main research project the hypothesis of anti-infective potential and resistance of MAIT cells to xenobiotics is applied to clinical practice in the field of haematooncology. The thesis presents evidence for a protective role of MAIT cells during the...
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Helminths in the mammalian lungs: migration strategies and pathology
Butula, Dan ; Majer, Martin (advisor) ; Novák, Jan (referee)
This bachelor thesis summarizes the knowledge about the migration strategies of medically important pulmonary helminths and their laboratory models and describes the pulmonary pathology caused by these helminths. Helminths typically enter the lungs within hours or days after infection and often migrate from the lungs to other body organs. Certain species migrate through the lungs intravascularly (schistosome larvae and in certain cases filarial larvae), but others enter the lung parenchyma directly (roundworm larvae, Strongyloides hookworms, adults of Paragonimus flukes, and the metacestode of the tapeworm Echinococcus) or colonise the pleural cavity (adults of Litomosoides sigmodontis and young adults of Paragonimus flukes). This, together with the time spent in the lungs, influences the pathology caused. During this time, mechanical damage to the lung tissue, granuloma formation, infiltration of immune cells, emphysema formation, remodelling of lung tissue and blood vessels, and more can occur. Excretory secretory products of helminths contribute significantly to the pathology, which, among other things, are used as a tool to modulate host immunity and shape the migratory pathway through the lungs. This topic is of particular importance in terms of elucidating the pulmonary processes that are...
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