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Drug interactions of cardiovascular drugs and their analysis in the patients of community pharmacy
Vávrová, Zuzana ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
Drug interactions of cardiovascular drugs and their analysis in the patients of community pharmacy Author: Zuzana Vávrová1 Tutor: PharmDr. Josef Malý, Ph.D.1 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové Introduction: Drug interactions represent a serious health problem and they cause many hospitalizations. Although their identification and documentation received a considerable attention, they remain unrecognized for many patients. Objectives: The goal of the thesis was to analyze serious drug interactions between cardiovascular drugs, to describe their management in clinical practice, which is useful during dispensation, and to evaluate occurrence of these drug interaction in a community pharmacy. Methodology: The information was gained from several databases and compared, and afterwards management of major drug interactions of betablockers and calcium channel blockers was created. Patients of a community pharmacy were screened for these drug interactions. The data were processed by frequency analysis. Results: In the theoretical part, 94 drug interactions were analysed. The total number of patients who received betablockers or calcium channel blockers in the community pharmacy was 525. Serious drug interactions described in this...
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Analysis of care in patients at risk for arterial hypertension in pharmacy II.
Panáčková, Kateřina ; Malý, Josef (advisor) ; Marešová, Helena (referee)
Analysis of care in patients at risk for arterial hypertension in pharmacy II. Author: Kateřina Panáčková Tutor: PharmDr. Josef Malý, Ph.D.1 Consultant: PharmDr. Stanislav Havlíček2 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové 2 Pharmacy Luna, Plzeň Introduction: Arterial hypertension is one of the most common illnesses in the Czech Republic. Not only this should be the reason for proper health education and early detection of clients endangered by this illness. Objectives: The objective of the thesis was to perform and evaluate consultancy activities in a pharmacy focusing on clients with a risk of arterial hypertension or with already diagnosed arterial hypertension. Methodology: Collection of data took place in a public pharmacy in Česká Lípa between 1 May 2013 and 27 June 2014. Measuring of blood pressure was a part of controlled interview with clients of the pharmacy. Following data was recorded into a form: social-demographic characteristics of the respondend, his/her attitude towards measuring blood pressure in the pharmacy, incidence of risk factors of arterial hypertension, respectively atherosclerosis and other illnesses in the anamnesis, medication including nutrition supplements, results of own measurings and proposed...
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Analysis of care in patients at risk for arterial hypertension in pharmacy IV.
Kotlanová, Lada ; Malý, Josef (advisor) ; Mareček, Aleš (referee)
Analysis of care in patients at risk for arterial hypertension in pharmacy IV. Author: Lada Kotlanová Tutor: PharmDr. Josef Malý, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague Introduction and aim: Arterial hypertension (AH) belongs due to its pressure and atherosclerotic complications among very serious global health problems. The main goal of the therapy of AH is to prevent these complications, comprising early diagnosis and proper treatment plan. The aim of the study was to realize counselling in a pharmacy focused on clients with the risk of AH or already diagnosed AH. Metodology: Data were collected in a community pharmacy in Kralovice from September 2014 to January 2015. Prior to blood pressure measurement, the controlled interview was conducted with each client using special form which enabled to obtain important data from clients' history. Following data were obtained: socio-demographic characteristics of each client; their relationship to blood pressure measurement; risk factors of AH or atherosclerosis, respectively; disease history and use of drugs including food supplements. Results of blood pressure measurement, proposed intervention, or drug related problems were also subsequently recorded into the form thus...
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Analysis of the effect of pharmacotherapy on the risk of a fall I.
Šturcová, Klára ; Malý, Josef (advisor) ; Doseděl, Martin (referee)
Analysis of the Effect of Pharmacotherapy on the Risk of a Fall I. Author: Klára Šturcová1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Pague Introduction: Falls of hospitalized patients are one of the most common problems in health institutions. In terms of prevention of falls it is necessary to analyze all the factors that might have contributed to the emergence of a fall and subsequently minimize these risk factors. Objectives: The aim of the thesis was to analyze the possible drugs and other causes of falls of patients hospitalized in a certain rehabilitation institution. Methods: The data were collected from 21 March to 31 July 2014 in an institution providing rehabilitation care. The evaluated group consisted of patients who fell during the hospitalization in this period. The data about the fall, personal and drug anamnesis were transferred to an electronic form and subsequently evaluated by means of the frequency analysis, converted into graphs and tables and discussed. Results: 67 patients experienced 79 falls. Women experienced 53 % of falls; men experienced 47 % of falls. 87 % of the patients fell once, 9 % of the patients fell twice, 4 % of the patients fell three times. 58 % of all falls were experienced by...
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Analysis of Possibility of Applying Clinical pharmacy to Pharmaceutical Care
Malý, Josef ; Vlček, Jiří (advisor) ; Šmahelová, Alena (referee) ; Halačová, Milada (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Kralove Department: Social and Clinical Pharmacy Candidate: Josef Maly Supervisor: Jiri Vlcek Tittle of Doctoral Thesis: Analysis of possibility of applying clinical pharmacy to pharmaceutical care Introduction and Aim Clinical Pharmacy (CP) is a modern, scientific, and multidisciplinary oriented medical field located on the border between pharmacy and medicine. CP follows the patterns and factors affecting the rational selection and use of drugs, dietary supplements, and medical devices used to health protection and the disease prevention and treatment. CP utilizes the methods and research outputs of other disciplines (e.g. pharmacology, pharmacoepidemiology, pharmacoinformatics, pharmacoeconomics, social pharmacy, or medical disciplines). The principles of CP may involve all pharmacists working in various types of health facilities. Furthermore, in practice the ideas of PC are developed by pharmaceutical care (PC). The aim of PC is to promote the optimal therapeutic value of prescribed drugs and OTC (over-the-counter), i.e. to reduce drug related problems (DRP) in the sense of maximization effect and minimization risk of therapy at optimal health care costs. DRP is defined as an event or circumstance associated with drug therapy that...
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Opinions, knowledge, perception of risks and compliance of patients using non-prescription drugs and dietary supplements I.
Obrová, Hana ; Malý, Josef (advisor) ; Doseděl, Martin (referee)
Opinions, knowledge, perception of risks and compliance of patients using non-prescription drugs and dietary supplements I. Author: Hana Obrová1 Tutor: Josef Malý1 1 Department of Social and Clinical Pharmacy, Charles University in Pague, Faculty of Pharmacy in Hradec Králové Introduction: A part of the health knowledge everyone of us should be the self-medication. The assortment of OTC drugs and dietary supplements is still being spread in the Czech Republic. It carries benefits and risks. Objectives: The aim of the study was to investigate current opinions, attitudes and knowledge of patients from the Czech Republic about OTC drugs. Methods: The data were collected at the hospital in Svitavy and at the Department of occupational medicine in Svitavy. The interviews were performed in April and July 2013. The data were analysed and described by means of the frequency analysis in Microsoft Excel 2007. Results: The answers were obtained from 169 respondents (44,0 % women and 56,0 % men). The average age of the patients was 50 years. 54,0 % of the patients preferred self-medication before the visit of the doctor. 85,0 % of the patients used at least one OTC drug in the last year. 77,0 % of the patients agreed with the statement that the self-medication could have some risks. The...
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Analysis of care in patients at risk for arterial hypertension in pharmacy I.
Gregor, Stanislav ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
Analysis of care in patiens at risk for arterial hypertension in pharmacy I. Author: Stanislav Gregor1 Tutor: Josef Malý1 Consultant: Stanislav Havlíček2 1 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové 2 Czech Chamber of Pharmacists, Prague Introduction: Arterial hypertension represents a serious health problem. Despite of the fact that great attention is paid to an early diagnosis and therapy of arterial hypertension, it remains compensated insufficiently in a number of patients. Objectives: The aim of the thesis was to analyse the possibilities of pharmaceutical care provided to patients who are at risk of arterial hypertension. Methodology: Blood pressure was measured from the beginning of October till December 2012 in a public pharmacy in Moravská Třebová. The blood pressure was measured by a pharmacist by means of a validated and calibrated tonometer. Other data were collected from a directed interview with the pharmacy client. The data were evaluated in Microsoft Excel 2007 and processed by means of the frequency analysis. A retrospective analysis of drug problems was further performed in patients who have been using pharmacotherapy or food supplements. Results: The data were obtained from 196 pharmacy clients (31 % of men and...
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Arterial hypertension - patients point of view in the public pharmacy
Jonášová, Iveta ; Rudolf, Kamil (advisor) ; Malý, Josef (referee)
Arterial hypertension - patients point of view in the public pharmacy Author: Iveta Jonášová ¹ Tutor: MUDr. PharmDr. Kamil Rudolf, Ph.D. ¹ š ¹ Department of Clinical and Social Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové š University Hospital Hradec Králové Background: The thesis deals with pharmacotherapy of arterial hypertension. Arterial hypertension is one from the most common diseases of the cardiovascular system. Current therapy and control over arterial hypertension are not sufficient, despite of progress in pharmacotherapy and introduction of new antihypertensive drugs into medication. Aim of study: Aim of this study was to find a deeper knowledge of hypertonic patients about their disease, their compliance with therapy and doctor's instructions and pacient's knowledge about their actual blood pressure. Effect of antihypertensive therapy was assessed including conformity local prescribing with current guidelines. Methods: Data of the prospective study were collected by a questionnaire. The exploratory sample was consisted of randomly 320 surveyed hypertensive patients living in the Štětí and its surroundings. The research was performed from July 2010 to November 2011. The questionnaire consisted of two respondent characteristics (sex, age) and 7 targeted...
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Adherence in patients with diabetes mellitus 2. type
Pavlatová, Jana ; Matoulková, Petra (advisor) ; Malý, Josef (referee)
ADHERENCE IN PATIENTS WITH DIABETES MELLITUS 2. TYPE Student: Pavlatová, J. Tutor: Matoulková, P. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic Introduction: Perceptions have been associated with medication adherence. Medication beliefs are explored with the use of the Beliefs about Medication Questionnaire (BMQ). Medication beliefs have been associated with underuse of antihyperglycemic medications in patients with diabetes mellitus 2. type. Czech translation of the BMQ has been validated in the cohort of chronicaly ill patients. Aim of the study: To identify medication beliefs in the patients with diabetes 2. type, to estimate adherence with medications in those patients. To identify whether there is medication underuse because of cost. Methods: Consecutive patients with type 2 diabetes who came to fill the prescriptions in the two pharmacies in Kostelec nad Orlicí during October - December 2011. Those patients were asked to fill the questionnaire that consisted of the BMQ-specific scale, MARS (Medication Adherence Report Scale) and additional background questions. Results: 73 patients with diabetes type 2 were identified and 41 filled the questionnaire. There was no medication undersue because of cost. Mean age was...
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