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Effectiveness of disinfectants for hygienic hand disinfection against clinically important strains of enterococci
Malíková, Martina ; Janďourek, Ondřej (advisor) ; Konečná, Klára (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Study program: Bioanalytical laboratory diagnostics in health care Candidate: Bc. Martina Malíková Thesis supervisor: PharmDr. Ondřej Janďourek, Ph.D. Consultant: RNDr. Irena Hanovcová, CSc. Title of diploma thesis: Effectiveness of disinfectants for hygienic hand disinfection against clinically important strains of enterococci Alcohol-based hand disinfectants for hygienic hand disinfection are a key tool for the control of nosocomial infections worldwide. The aim of this study was to verify the effectiveness of these products, which are used in healthcare facilities, against vancomycin-sensitive and vancomycin-resistant enterococci isolated from clinical materials. Testing of the efficacy of disinfectants was performed according to the Czech technical standard ČSN EN 1040 - Chemical disinfectants and antiseptics - Quantitative test using suspension to determine the basic bactericidal effect of chemical disinfectants and antiseptics - Test method and requirements (phase 1). We used the dilution method with a neutraliser for our testing. There were used a total of 35 strains of enterococci to determine efficacy, 12 of which were vancomycin sensitive (four E. faecium strains and eight E. faecalis...
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Effectiveness of disinfectants for hygienic hand disinfection against clinically important strains of enterococci
Malíková, Martina ; Janďourek, Ondřej (advisor) ; Konečná, Klára (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Study program: Bioanalytical laboratory diagnostics in health care Candidate: Bc. Martina Malíková Thesis supervisor: PharmDr. Ondřej Janďourek, Ph.D. Consultant: RNDr. Irena Hanovcová, CSc. Title of diploma thesis: Effectiveness of disinfectants for hygienic hand disinfection against clinically important strains of enterococci Alcohol-based hand disinfectants for hygienic hand disinfection are a key tool for the control of nosocomial infections worldwide. The aim of this study was to verify the effectiveness of these products, which are used in healthcare facilities, against vancomycin-sensitive and vancomycin-resistant enterococci isolated from clinical materials. Testing of the efficacy of disinfectants was performed according to the Czech technical standard ČSN EN 1040 - Chemical disinfectants and antiseptics - Quantitative test using suspension to determine the basic bactericidal effect of chemical disinfectants and antiseptics - Test method and requirements (phase 1). We used the dilution method with a neutraliser for our testing. There were used a total of 35 strains of enterococci to determine efficacy, 12 of which were vancomycin sensitive (four E. faecium strains and eight E. faecalis...
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Age management vo vybranej firme
Malíková, Martina
Malíková, M. Age management in selected company. Bachelor thesis. Brno: Mendel University in Brno, 2020. The bachelor thesis deals with the current situation of the company, its surroundings and proposals of age management. The aim of this thesis is to propose the application of the age management in the company and make the control of human resources effective. The thesis is divided into two parts. In theoretical part is described the demographic situation in Czech Republic and in Slovakia, population aging, unemployment, diversity and diversity management, age management and discrimination. Analytical part consists of quantitative and qualitative research. Suggestions to implement age management and making the control of human resources in company more effective are based on questionnaires and interview with employee of the company. Recommended suggestions are economically calculated in the conclusion of the bachelor thesis.
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Sensitivity testing of vankomycin resistant and vancomycin sensitive enteroccoci on selected biocides
Malíková, Martina ; Janďourek, Ondřej (advisor) ; Voxová, Barbora (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Study program: Healthcare bioanalytics Candidate: Martina Malíková Thesis supervisor: PharmDr. Ondřej Janďourek, Ph.D. Consultant: RNDr. Irena Hanovcová, CSc. Title of bachelor thesis: Testing the sensitivity of vancomycin-resistant and vancomycin-sensitive enterococci on selected biocides Vancomycin resistant enterococci (VRE) are one of the most common causes of nosocomial infections. The aim of this work was to determine the sensitivity of vancomycin-resistant and vancomycin-sensitive enterococci to selected biocides, which are part of disinfection programs in healthcare facilities. When testing the effectiveness of disinfectants, we followed the Czech technical standard ČSN EN 1040 - Chemical disinfectants and antiseptics - Quantitative suspension test to determine the basic bactericidal effect of chemical disinfectants and antiseptics - Test method and requirements (Phase 1). We used a dilution method with a neutralizer. We tested a total of 10 Enterococcus faecium strains. Four out of the 13 biocides tested were completely effective. These were agents with a higher concentration of aldehydes, with peracetic acid and active chlorine. We observed different efficacy in individual strains for...
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