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Quality of life after urogynecologic surgery Comparation of change of quality of life after urogynecologic surgery in relation to anatomy of the pelvis foor
Drahorádová, Petra ; Mašata, Jaromír (advisor) ; Zachoval, Roman (referee) ; Naňka, Ondřej (referee)
Introduction: Stress urinary incontinence is a common problem which affects a high percentage of women. Anti-incontinent surgery has played an important role in the treatment of stress urinary incontinence. Burch colposuspension was considered a gold standard in anti-incontinence surgery, with good long-term results. However, over the past decade this procedure has been largely replaced by the application of various types of TVTs (tensionfree vaginal tapes). In our study we have focused on comparing developments in the quality of life and the occurrence of complications in a long-term follow-up after TVT, TVT O and colposuspension. For subjective assessment of urinary incontinence we have chosen a validated specialized Incontinence Quality of Life questionnaire (I-QoL). The aim of our study was to monitor the trends with quality of life after TVT, TVT O and colposuspension procedures and to establish whether the occurrence of complications affects the quality of life (QoL) and compare of the quality of life among anti-incontinence procedures and longterm subjective and objective outcome. Methods: The study included 215 women who underwent a TVT, TVT O or Burch procedure between 1.6.2002 - 31.5.2005. Women were completely urogynecologic examined and urodynamic stress incontinence was documented....
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Variation of abnormalities of foramen obturatum and retropubic space and its relation to complications of tape surgery
Hubka, Petr ; Mašata, Jaromír (advisor) ; Smetana, Karel (referee) ; Krofta, Ladislav (referee)
Introduction: The knowledge of anatomy is crucial for introduction of new surgical methods. It is also of especial use while dealing with surgical complications during surgeries with limited surgical field, where the way of approach limits the management of complications. It was assumed that common anatomical variations would influence different efficacy of surgeries and would explain potential complications. Methods: During anatomical dissections fifty female cadavers were dissected and tension-free vaginal tapes TVT-S H, TVT-S U, TVT Abbrevo and Ajust were studied. A novel descriptive system for localisation of the tape was created. During the dissection the tape was located and its localisation and fixation was described. Results: Common anatomical variation in the sample was corona mortis with frequency of 72 %. Preperitoneal fatty plug, which is recognized by some authors as the first stage of obturator hernia, was found in 40 % in obturator canal. The proper fixation of TVT-S H was achieved in 53.6 %. In 10.5 % urinary bladder was injured. In case of TVT-S U the proper fixation occurred in 63.8 %. In two cases the inserter was nearby corona mortis. Within the group of TVTO Abbrevo the tape was fixated properly into the obturator complex (consists of the obturator membrane and obturator muscles) in...
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The influence of some xenobiotics from environment on the reproduction
Jirsová, Simona ; Mašata, Jaromír (advisor) ; Stárka, Luboslav (referee) ; Černá, Milena (referee)
The aim of this study: To confirm the possibility of detection of polychlorinated biphenyls (PCBs) and organohalogen pesticides (OCPs) in blood and follicular fluid of infertile women. To determine the levels of some congeners and to confirme their cumulation in follicular fluid and their influence on the results of IVF +ET program. Methods: We detected the levels of PCBs and OCPs at first in blood and follicular fluid of 30 infertile women. After that we analysed the relationship between the presence of these xenobiotics and achieving succesful pregnancy. Results: It was found the cumulation of this xenobiotics in follicular fluid. PCB 118+123, PCB 156, PCB 172, HCB (hexachlorobenzene) and beta HCH (hexachlorocyclohexane) are dependent on the age of patients. The most part of PCBs is also higher in patiens with high BMI (body mass index). We foud the higher concentrations of PCB 47 a PCB 158 in patients with primary sterility. This correlation was not statistically significant. We confirmed statistically significant higher levels of PCBs in folicular fluid of patients with endometriosis. The levels of OCPs didn't differ. A correlation has been ascertained between the number of diploid oocytes and the levels of DDT, fertilization of oocytes and levels of PCB 158 and the pregnancy rate and the number of...
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