National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Toxic compounds in a diet as a factor of chronic diseases
Logerová, Hana ; Dlouhý, Pavel (advisor) ; Černá, Milena (referee) ; Kouřimská, Lenka (referee)
Flame retardants have been used in the Czech Republic since the 1980s and 1990s as a part of the polymer matrix of plastic materials to decrease their combustibility and thus the risk of fire. Brominated flame retardants (BFR) are commonly used, polybrominated diphenyl ethers (PBDEs) are the most abundant flame retardants in plastic materials. The human population is exposed to these compounds particularly via diet containing fatty fish, meat and dairy products and via inhalation of dust particles. Another aspect is the duration of the exposure: it is known that human beings can be exposed to BFRs from infancy through prolonged breast feeding because breast milk can be contaminated by these compounds. This study was performed to investigate the concentrations of the main representatives of BFRs occurring in human adipose tissue and to compare these values with the concentration of chlorinated contaminants (PCBs, DDTs). The pollutants levels were newly measured in solid adipose tissue removed during surgery. A total of 107 samples of fat were taken from 19 - 76 year-old volunteers mostly obese women. A total of 16 PBDEs congeners were determined, of which only six occur in more than 38 % of fat tissue samples. The total PBDEs level attained an average value of 3.31 ng/g, which is 25 % less than was...

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