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Role of proteins of Bcl family on oncogyneacology
Lidová, Lenka ; Švandová, Ivana (advisor) ; Svoboda, Petr (referee)
The Bcl-2 protein family consists of about 20 homologues important for stimulation and inhibition of apoptosis. The ratio between pro- and antiapoptotic regulators predetermines fate of the cells. Apoptosis is a physiological form of cell death which plays an important role in tissue development and maintenance of tissue homeostasis. By the apoptotic way are eliminated redundant cells and cells which can damage the organism. Cells undergo apoptosis through two major apoptotic pathways - the extrinsic or the intrinsic apoptotic pathway. Apoptotic cells are characterised by specific changes - nuclear, plasma membrane, mitochondrial etc. The contents of dead cells are packaged into apoptotic bodies. These are then recognized by macrophages and cleared by phagocytosis. Dysregulation of apoptosis may lead to many malignant, autoimmune or degenerative diseases and some developmental defect. Understanding the mechanisms of apoptosis can be an important part of the diagnostics and therapy in oncology.
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Teaching students with specific learning difficulties focusing on science at high schools
Lidová, Lenka ; Rajsiglová, Jiřina (advisor) ; Kortová, Veronika (referee)
The specific learning difficulties (LD) are nowadays frequently discussed topic, which is still more current even at high schools. Teachers should help these students because of their learning difficulties. LD students are not stupid, they just need a little bit different approach in the classroom than the others. This thesis mainly shows various teachers' approaches to students with LD in different schools and different countries. Because I study teaching biology and chemistry, the work is focused on science subjects and on teachers of these subjects. The aim of this paper is also to propose the basic procedures of working with the LD students for high school teachers with the real ideas of possible adaptations in the science class. In order to discuss approaches to the work with LD students it was necessary to prepare an LD overview at first. To achieve the aims of the work we used methods such as literary research, questionnaire survey and interviews with teachers and students. The theoretical part summarizes basic information about various learning difficulties, different approach to LD students in science, the teachers' and classmates' attitudes to LD in various countries and different approaches to integration of LD students in various countries. The task of the practical part was to identify...
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Teaching students with specific learning difficulties focusing on science at high schools
Lidová, Lenka ; Rajsiglová, Jiřina (advisor) ; Kortová, Veronika (referee)
The specific learning difficulties (LD) are nowadays frequently discussed topic, which is still more current even at high schools. Teachers should help these students because of their learning difficulties. LD students are not stupid, they just need a little bit different approach in the classroom than the others. This thesis mainly shows various teachers' approaches to students with LD in different schools and different countries. Because I study teaching biology and chemistry, the work is focused on science subjects and on teachers of these subjects. The aim of this paper is also to propose the basic procedures of working with the LD students for high school teachers with the real ideas of possible adaptations in the science class. In order to discuss approaches to the work with LD students it was necessary to prepare an LD overview at first. To achieve the aims of the work we used methods such as literary research, questionnaire survey and interviews with teachers and students. The theoretical part summarizes basic information about various learning difficulties, different approach to LD students in science, the teachers' and classmates' attitudes to LD in various countries and different approaches to integration of LD students in various countries. The task of the practical part was to identify...
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Role of proteins of Bcl family on oncogyneacology
Lidová, Lenka ; Svoboda, Petr (referee) ; Švandová, Ivana (advisor)
The Bcl-2 protein family consists of about 20 homologues important for stimulation and inhibition of apoptosis. The ratio between pro- and antiapoptotic regulators predetermines fate of the cells. Apoptosis is a physiological form of cell death which plays an important role in tissue development and maintenance of tissue homeostasis. By the apoptotic way are eliminated redundant cells and cells which can damage the organism. Cells undergo apoptosis through two major apoptotic pathways - the extrinsic or the intrinsic apoptotic pathway. Apoptotic cells are characterised by specific changes - nuclear, plasma membrane, mitochondrial etc. The contents of dead cells are packaged into apoptotic bodies. These are then recognized by macrophages and cleared by phagocytosis. Dysregulation of apoptosis may lead to many malignant, autoimmune or degenerative diseases and some developmental defect. Understanding the mechanisms of apoptosis can be an important part of the diagnostics and therapy in oncology.
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Perception of the Elderly by the Students of the University of South Bohemia
LIDOVÁ, Lenka
Abstract This diploma thesis named "Perception of the Elderly by the Students of the University of South Bohemia" provides a detailed insight into the senior population viewed by the university students. The aim of this work is to register the students' attitudes and the opinions to this issue. The work consists of two parts a theoretical and the practical. The theoretical part deals with issue of ageing process, namely with the changes which are carried by this life period. Further, this part looks at personalities of university students and their needs in general. Next, it covers a general knowledge about interpersonal perception among humans. This part also describes problems of prejudices and stereotypes connected with a very actual issue ageism. The practical part of this diploma thesis contains an own qualitative research which includes a description of used methodology, examined sample, outcomes and further discussion. These data were collected during a field research in February 2014. It was used a technology of semantic differential. The research was undertaken within the University of South Bohemia. Students of Faculty of Theology, Faculty of Health and Social Studies, Faculty of Economy and Faculty of Agriculture were asked to take a part in this study. They expressed their opinions via a web portal www.mojeanketa.cz. These faculties were chosen deliberately for their different fileds of studies. Thus, I compared the opinions of the students whose fields of studies are specialized either on the market and the business sector, or whose fields of studies are specialized on the help professions and, therefore, their further practice will be orientated to the non-profit sphere. Within this study there were distributed 400 record sheets in total (100 for each faculty) where the responders expressed their opinions. The opinions on the perception of the elderly were expressed within the scale from 1 to 5. The values of this scale has been of a contradictory character. For instance, there were these characteristics: beautiful/ugly, noisy/calm, self-sufficient/un-self-sufficient etc. There was also stated a hypothesis which has been predicted that the students of the University of South Bohemia perceive the elderly positively. The research proved this expectation. The outcomes also show that there is no big difference between the individual opinions of the students of different faculties. This result is actually very positive and, therefore, we can say that the students of the University of South Bohemia do not display any prejudices and stereotypes towards the senior population. The outcomes of this work might be very beneficial as sources for educational work beyond ageism. Further, there can be reached conclusions which will lead to reflection. This work can be used for further scientific investigations and publication activity.
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Mutual perception of seniors and teenagers
LIDOVÁ, Lenka
The present bachelor thesis consists of two parts, theoretical and practical. Its theoretical part engages in the characteristics of growing up and aging, and describes pubescence, senescence, old age, with all changes that these life phases bring with them. Furthermore, it examines the problems of ageism or discrimination because of age. The practical part of the bachelor thesis is based on research and findings that were acquired in such research. The objective of the whole thesis was to determine - by means of a semantic differential - teenagers? opinions of seniors and vice versa. Our intention was to ascertain from respondents, who completed record sheets, if they are prejudiced in any way against the other generation and if they are influenced by stereotypes. Identical record sheets were prepared for both target groups, whereas these record sheets introduced contradictory traits of character., such as slow-fast, beautiful-ugly, tidy-untidy, communicative- uncommunicative and similar. Results of this evaluation of individual character traits performed by respondents reveal apparent differences. However, the overall findings show that both groups perceive each other positively. This bachelor thesis may be used for future publication activities and as potential documentation tackling the issues of ageism.
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