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Normative Study Of A Memory Test "FCSRT-IR" in Older Population
Horáková, Karolína ; Georgi, Hana (advisor) ; Kulišťák, Petr (referee)
The diploma thesis is focused on standardization of the neuropsychological test The Free and Cued Selective Reminding Test with Immediate Recall (FCSRT-IR), this test is a one of memory tests which contains phase with controlled learning. In the theoretical part it deals with aging and cognitive functions especially memory, further episodic memory test especially FCSRT-IR and its administration and benefits of this test against other episodic memory tests. In the practical part of this diploma thesis we report norms based on population in age 60 years and older (N= 362; range of age from 61 to 97), the norms are based on National Normative Study of Cognitive Determinants of Healthy Ageing which took place from 2012 to 2015 (IGA NT13145) and the author of this diploma thesis was a member of its team. In the second part of this thesis we deal with validation study which was conducted on population of people with dementia in Alzheimer's disease (N= 37; range of age from 61 to 88) comparing with healthy control group. In this validation study we confirmed that FCSRT-IR is a sensitive method for detection dementia in Alzheimer's disease. Keywords: Episodic memory, FCSRT-IR, controlled learning, norms, validation
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The Effect of Multimodal Method of Rehabilitation of Cognitive Functions using Computer-Assisted Program NEUROP Školitel: doc.
Pulkrabková, Alice ; Kulišťák, Petr (advisor) ; Georgi, Hana (referee) ; Jarolímová, Eva (referee)
Title: The Effect of Multimodal Method of Rehabilitation of Cognitive Functions using Computer-Assisted program NEUROP Author: Mgr. Alice Pulkrabková Department: Department of Psychology, Charles University, Faculty of Arts Supervisor: doc. PhDr. Petr Kulišťák, Ph.D. Abstract: Neuropsychological rehabilitation of cognitive functions is an important field of clinical psychology application. It can moderate brain damage sequelae and has a major impact on patients'quality of life. At present, with an improving medical knowledge and care, we are able to cure previously fatal conditions. That is associated with the fact, that a number of people who are facing the cognitive impairment is steadilly growing. Therefore it is important to develop new methods of rehabilitation of cognitive functions and to assess their effectivity. In our thesis we outline the theoretical background of rehabilitation of cognitive functions and map different types of interventions. The main goal is to assess the effectivity of our group multimodal complex cognitive training program. It combines the conventional methods of cognitive rehabilitation with a computer-assisted program NEUROP and education. The program is designed for a small group of max. 10 patients. The length of the program is 8 weeks, with 2 weekly sessions (2x 40 mins...
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Evaluation of Psychometric Characteristics of Czech Version RBANS
Brodská, Veronika ; Krámská, Lenka (referee) ; Kulišťák, Petr (referee)
The thesis deals with the Czech version of the original American neuropsychological battery RBANS (i.e. Repeatable Battery for the Assessment of Neuropsychological Status). There are two objectives of the thesis: verifying the test-retest stability and assessment of the equivalency of the two alternate forms, form A and B of the Czech version of the RBANS. The theoretical part deals with neuropsychological diagnostics and its methods, it also presents a neuropsychological battery RBANS, describes a test method, testing materials and organization of the scale, and it reminds RBANS use in clinical practice through a number of foreign studies. The practical part analyse data that were obtained from the group of 46 healthy volunteers aged between 20 and 77 years by repeated administration of the method. The time period between test and retest was 1 month. The test-retest stability was evaluated by the coefficient of stability and the equivalence of forms A and B by a coefficient of equivalence. Furthermore, there were evaluated possible correlations with the level of education and age. The test-retest coefficients of stability were in total score of 0.75 and 0.71 and they ranged from 0.43 to 0.85 in indexes; and equivalence coefficients were in total score of 0.72 and 0.71 and they ranged from 0.43 to 0.87 in...
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The Ecological Validity of the Tests of Executive Functioning in Patients with Schizofrenia
Drozdová, Kristýna ; Kulišťák, Petr (advisor) ; Krámská, Lenka (referee) ; Bahbouh, Radvan (referee)
Aim: The current study investigated a pattern of associations between executive functions and everyday functioning in a sample of schizophrenia patients with the aim to specify the ecological validity. The ecological validity as a specific form of external validity refers to the extent of the relation of the test outcome measures and patients' behaviour in everyday situations. Sample and methods: A sample of 77 patients (22 women and 55 men) with the diagnosis of schizophrenia or schizoaffective disorder, who met study inclusion criteria, was assessed with several executive function tests: Wisconsin Card Sorting Test (WCST), Trail Making Test B (TMT B), Phonemic Verbal Fluency Test and Semantic Verbal Fluency Test (VF), Similarities from Wechsler Adult Inteligence Scale (WAIS III), Rey-Osterrieth Complex Figure Test in Boston Qualitative Scoring System (BQSS), and with rating scales for patients' behavior in everyday situations - Personal and Social Performance Scale (PSPs), newly developed clinical scale (CliSca), Interview for Assessment of Insight (SAI) and patients' self rating in Social Functioning Scale (SFS). Relationships between demografic measures and test outcomes were examined. Results: Verbal fluency tests did correlate significantly with the newly developed clinical scale that seems...
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Mirror neurons and language in schizophrenia
Bendová, Marie ; Kulišťák, Petr (advisor) ; Loneková, Katarína (referee)
Mirror neurons are a specific kind of visuomotor neurons that are involved in action execution and also in action perception. The mirror mechanism is linked to a variety of complex psychological functions such as social-cognitive functions and language. People with schizophrenia have often difficulties both in mirror neuron system and in language skills. In the first part of our research we studied the connectivity of mirror neuron areas (such as IFG, STG, PMC, SMC and so on) by fMRI in resting state and the differences between a group of patients during first episode psychosis and a group of healthy controls. The second part of our research was dedicated to language: if there are specific activations in certain parts of the cortex (such as SMC, Broca's and Wernicke's areas) along with a specific meaning of the word stimuli and if these activations are disrupted in patients with schizophrenia. The first part of the research showed a significant difference in the mirror neuron system connectivity between these two groups. The patients had stronger connections between the thalamus (which mediates sensory information) and the cortical areas while the controls had the cortical areas more interconnected. The second part of our research, a language experiment, showed significant differences between the...
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Vascular changes and hippocampal atrophy in Enhanced Cued Recall test
Vaníčková, Monika ; Kulišťák, Petr (advisor) ; Šivicová, Gabriela (referee)
Memory structure, memory assessment, Grober-Buschke paradigm, Alzheimer disease, and vascular dementia were discussed in the first part of the present thesis. Present study aims to examine the relationship between white matter changes, hippocampal atrophy and the performance in Enhanced Cued Recall test in nondemented geriatric population (n = 104). Partial neparametric correlations were used while controlling for age and Fazekas score. Medium correlations were found between left/right hippocampal volumes and free and total recall. No correlations were found between Fazekas score and ECR scores while controlling for age and left and right hippocampal volumes. Keywords: hippocampal atrophy, white matter changes, cued recall, ECR
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Effects of electroconvulsive therapy on cognitive functions
Kubinová, Markéta ; Šivicová, Gabriela (advisor) ; Kulišťák, Petr (referee)
(in English): Electroconvulsive therapy (ECT) is a very effective treatment procedure for patients with severe and treatment resistant psychiatric disorders. This Thesis deals with the impact of electroconvulsive therapy on cognitive function, specified as a measurement of cognitive function after electroconvulsive therapy, focusing on the monitoring of cognitive function, eventually their deficits with the passage of time after ECT. At several time points (T1 week after ECT completion; T2: 6-8 weeks after ECT completion) from ECT completion the progression of cognitive performance of patients was repeatedly measured. Respondents were divided according to their diagnosis (mood disorders groop and schizophrenia group). The groups were compared with each other. The aim of the Thesis is the observance of the cognitive changes in patients over time after electroconvulsive therapy. In the final stage 18 subjects were submissed into the study (10 women and 8 men). In terms of diagnosis 39% were diagnosed with the disease in the ICD category F20-F29; 33% were diagnosed with mood disorders (category ICD: F30-F39) and 28% were diagnosed with F06.3 organic affective disorder. The MCCB (MATRICS Consensus Cognitive Battery) was chosen as a method for data scan, it has very good psychometric properties also...
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Profiles of cognitive deficit and the use of a short neuropsychological battery in different types of dementia
Bolceková, Eva ; Kulišťák, Petr (advisor) ; Krámská, Lenka (referee) ; Jirák, Roman (referee)
Pro les of cognitive de cit and the use of a short neuropsychological battery in di erent types of dementia Eva Bolceková Abstract This work focuses on cognitive de cit pro les and the use of a short neuropsychological battery in patients with di erent types of dementia. Increasing prevalence of dementia syndromes highlights the need of their e cient diagnostics in clinical-psychological practice. Theoretical part of this work presents an overview of neurodegenerative diseases with em- phasis on their neuropsychological presentation. We describe the cogni- tive domains and their neuropsychological examination. We address in detail the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and its experimental Czech version. Research part of the work is based on neuropsychological examinations of 311 patients with cognitive de cit and 118 healthy controls. Patients' group is comprised of subjects with Alzheimer's disease, mild cognitive impairment, vascular cognitive impairment, Lewy Body disease, frontotemporal lobar degene- ration and patients with depression. We assess their cognitive pro les, present sensitivity, speci city, positive and negativne predictive values of RBANS scores for the groups and compare the results of control subjects with the original normative sample. We...
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