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Significance of adjuvant radiotherapy in malignant mesenchymal tumors of the uterus
Němčíková, Petra ; Kubecová, Martina (advisor)
Malignant mesenchymal tumors of the uterus occur in 2-5%, but the incidence varies from 1-3/100 000 women. Characteristic of uterine sarcomas are aggressive growth and early metastasis blood and lymphatic route, low-grade leiomysarkom (LMS), endometrial stromal sarcoma (ESS) and adenosarkom may be long intervals when a woman does not have any problems. Most commonly occurring sarcoma is carcinosarcoma, which represents 47-60% of cases. It occurs mainly in postmenopausal women. Clinically, abnormal uterine bleeding, abdominal pain, stinking discharge. Carcinosarcoma rapidly metastasizing, at the time of primary surgery is now often extended beyond the uterus and has the worst prognosis. Five-year survival is between 2-9%. Another is in the order Leiomyosarcoma (LMS), which occurs in about 30-38% of cases. Usually arises de novo and is solitary, rarely arises transform in benign myoma. His prognosis is better. In a classic example of clinical manifestation of the states rapidly growing fibroid. However, it was shown that only 1% of hysterectomies, as indicated by the rapidly growing fibroid is histologically proven LMS and only 2.6%. LMS is diagnosed on the basis of hysterectomy, indicated for suspected (fast growing) myoma. Endometrial stromal sarcoma (ESS) are approximately 10-25% of cases and is usually...
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