|
|
Differential Diagnostics of Anaemias from the Morphological Point of View
KLIMENTOVÁ, Michaela
Anaemia is considered to be a worldwide disease and it remains to be a topical one. This thesis tries to stress the importance of correct diagnosis of anaemia, without which correct and effective treatment cannot be adjusted. Although the number of people with anaemia is increasing, a large proportion are unaware of their disease, have not been diagnosed with it and therefore do not treat it. To diagnose anaemia is not difficult, however, differential diagnosis is the key to diagnose it correctly. A great contribution to the differential diagnosis is the description of erythrocyte indices that can be used to determine the exact type of anaemia and their subsequent use in differential diagnosis. The main objective of this bachelor thesis, entitled "Morphological Differential Diagnosis of Anaemia", is the statistical evaluation of the incidence of different types of anaemia, differentiated based on the erythrocyte morphology. Within the practical part of the thesis, blood counts were analysed on an automatic haematology analyser and then the data from the examinations were statistically processed. Excel was used to process all the data. The results of the statistical processing were entered into tables and graphs. Before the statistical processing, 3 hypotheses were defined and tested using a chi-square test which resulted in a level of significance (p). For all three hypotheses, the resulting level of significance was <5%, meaning that all null hypotheses were rejected and in all cases the alternative hypothesis was accepted. Surprisingly, macrocytic anaemia was more frequent than microcytic anaemia in the dataset (20 % of all types of anaemia versus 10 %), but as expected, hypochromic anaemia was more frequent than hyperchromic anaemia (17.39 % of all types of anaemia versus 5.65 %). Normocytic normochromic anaemia was the most represented anaemia in the dataset (62.61 % of types of anaemia). The results obtained from this study may be used for research purposes or as a source of information.
|
guest ::
RSS feed.