National Repository of Grey Literature 6 records found  Search took 0.01 seconds. 
The antioxidant and Hormonal Effects of Ginseng Panax on Lifespan and Stres Resistance in Caenorhabditis elegans
Ježek, Václav ; Tůmová, Lenka (advisor) ; Martin, Jan (referee)
The Thesis: The Antioxidant and Hormonal Effects of Ginseng Panax on Lifespan and Stress Resistance in Caenorhabditis elegans Made by: Václav Ježek The antioxidant and hormonal effect of Panax ginseng on lifespan and stress resistance in C. elegans were investigated. The best results by treatment of C. elegans were achieved in the presence of pure GPE 50 µg/ml without the presence of cholesterol. Surprisingly this medium assigns the increase of mean survival by 10.98 % in contrasting with medium containing the mixture of GPE 50 µg/ml and cholesterol. This negative impact of GPE and cholesterol co- administration on lifespan of C. elegans is more obvious by using sixfold higher concentration of GPE (300 µg/ml). In this case the increase of mean survival by treatment with pure GPE is 17.69 %. In addition the highest increase of progeny was observed in medium with pure GPE 300 µg/ml. Surprisingly this concentration was appointed as toxic with negative effect on lifespan of C. elegans. It is obvious that GPE does not protect C. elegans against oxidative stress significantly because it does not suppress the expression of hsp-16.2/GFP and does not protect against oxidative stress caused by lethal dose of juglone. These findings suggest that the antioxidant activity of GPE does not play prevailing role by...
The historical and archaeological importance of travel accounts made by Russian pilgrims to the Near East from the 12th to 19th centuries.
Ježek, Václav ; Tumis, Stanislav (advisor) ; Boček, Pavel (referee) ; Nykl, Hanuš (referee)
This work deals with a theme, which is increasingly becoming popular amongst scholars. It is a theme dealing with Russian pilgrims and travellers, who visited the areas of the Middle East, especially those places, such as Constantinople, the Holy Land, Mt. Athos and others. Under the designation Russian pilgrims we do not mean individuals belonging to a specific ethnic group, but individuals who were related to Russia understood as a political formation and state. The contacts between the south and Russia, have important consequences for the development of Russia itself, its culture, identity and history. This is also the case for the Middle East, where the contacts with Russia determined to a large extent the development and character of this area. The Russian contacts with the south should be primarily viewed in terms of the Byzantine-Russian context. These were based on cultural influences and on a shared faith and identity. The cultural and religious contacts were enabled by travelling individuals, who travelled without and with a specific goal. In the context of these journeys the prime motivation was a religious one, when a pilgrimage to such areas as Constantinople, Mt. Athos, the Holy Land, helped to build a religious identity in Russia, since before the fall of Constantinople, religion...
Awareness of high school students about visual impairmant and comunication to persons with visual disabilities
Veselá, Michaela ; Vojtíšek, Petr (advisor) ; Ježek, Václav (referee)
(in English): My bachelor's work deals with awareness of high school students about visual impairment and communication to person with visual disabilities. The aim of the thesis is to find out a degree of high school students awareness about visual impairment which are closely related to sympathy, acceptance and consequent way of knowledge of eye disorders for contemporary and future secondary school students and the young generation in our society. The thesis is divided into two parts, theoretical and practical ones. The first part introduces readers into the issues about visual impairment, defines the elemental terminology, describes and classifies eye disorders, deals with the causes of disabilities and impacts about visual impairment, on personal and social sphere. The first part is also dedicated to the communication with individuals with eye handicap, using compensatory tools and rehabilitation of the visually impaired persons. The second, practical part researches the high school students awareness of the issues about visual impairment. It is focused on the students' knowledge of services area, communication and accompaniment and help to visually impaired people and using of compensatory tools. Onwards, the second part presents the high school students personal experience with visually...
The antioxidant and Hormonal Effects of Ginseng Panax on Lifespan and Stres Resistance in Caenorhabditis elegans
Ježek, Václav ; Martin, Jan (referee) ; Tůmová, Lenka (advisor)
The Thesis: The Antioxidant and Hormonal Effects of Ginseng Panax on Lifespan and Stress Resistance in Caenorhabditis elegans Made by: Václav Ježek The antioxidant and hormonal effect of Panax ginseng on lifespan and stress resistance in C. elegans were investigated. The best results by treatment of C. elegans were achieved in the presence of pure GPE 50 µg/ml without the presence of cholesterol. Surprisingly this medium assigns the increase of mean survival by 10.98 % in contrasting with medium containing the mixture of GPE 50 µg/ml and cholesterol. This negative impact of GPE and cholesterol co- administration on lifespan of C. elegans is more obvious by using sixfold higher concentration of GPE (300 µg/ml). In this case the increase of mean survival by treatment with pure GPE is 17.69 %. In addition the highest increase of progeny was observed in medium with pure GPE 300 µg/ml. Surprisingly this concentration was appointed as toxic with negative effect on lifespan of C. elegans. It is obvious that GPE does not protect C. elegans against oxidative stress significantly because it does not suppress the expression of hsp-16.2/GFP and does not protect against oxidative stress caused by lethal dose of juglone. These findings suggest that the antioxidant activity of GPE does not play prevailing role by...
MacIntyre´s concept of the development of ethics in modern times
JEŽEK, Václav
Diploma thesis deals with the analysis of the book by Alasdair MacIntyre ?After virtue. A Study in Moral Theory ? in which the author discusses the crisis of moral values at the time of Modern Period. The main part of the thesis is devoted to this book and also the views of scholars from Classical times up to the early 20th century. The thesis is divided into five chapters. The first chapter deals with the thoughts of Alasdair MacIntyre, the second chapter discusses emotivism, the third chapter contains an essay on the topic of virtues and examines how values changed and develioped in society throught the ages. The fourth chapter questiones the Modern period and the crisis of values in this time. The fifth chapter is an essay about Friedrich Nietzsche.
Questions of Needs of Elderly People with Visual Impaired
JEŽEK, Václav
The theoretical part charactrises groups of visual acuity, mostly eye diseases in elderly people, mostly needs elderly people with visually impairment, global rehabilitations of the seniors with visually impairment, special optical aids and compensation aids for visually impairment and social services and social benefits for seniors with visually impairment.Teoretical part of this workconserning seniors with visually impairmend has a edition practical part with report of pilot study provided at the Low Vision Clinic of the Faculty Hospital Motol in Prague.

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