National Repository of Grey Literature 62 records found  beginprevious36 - 45nextend  jump to record: Search took 0.00 seconds. 
Molecular mechanisms affected by n-3 polyunsaturated fatty acids
Hensler, Michal ; Flachs, Pavel (advisor) ; Rossmeislová, Lenka (referee) ; Dlouhý, Pavel (referee)
Adipose tissue and its hormones have an irreplaceable role in the physiology of mammals. The imbalance between energy intake and energy expenditure leads to the expansion of adipose tissue and changes in its secretion profile. With obesity are associated diseases including cardiovascular diseases, dyslipidemia, hypertension and insulin resistance, one of the major public health issues. Long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) from marine origin, mainly eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids exert numerous beneficial effects, such as improvements of lipid metabolism and prevention of obesity and diabetes. Studies with obesity-prone model mice (C57BL/6) provide us important knowledge regarding their effect on mammalian tissues and to test potential therapeutic interventions. The thesis is based on five published studies (A-E). Three studies are focused on white adipose tissue. In these works we proved that adipose tissue is a flexible organ and LC n- 3 PUFAs are potent regulators of adipose tissue biology. Our results document that LC n- 3 PUFAs affect adipose tissue mass by a mechanism, which depends on counteraction of both, differentiation and proliferation of adipose cell (publication A). The anti-obesity effect of EPA and DHA could be magnified by mild calorie...
Patient's compliance of dietary therapy in metabolic disease
Potočková, Jana ; Anděl, Michal (advisor) ; Dlouhý, Pavel (referee)
The goal of my bacalaureat thesis is an assessment of compliance of the patients with selected metabolic disorders treated by the diet. As an example of these disease most common civiliza- tion diseases as a diabetes mellitus, several types of hyperlipoproteinaemias and obesity were selected Treatment of these disorders is based mostly on the whole life regimen of the diet and life organization. Well accepted compliance is the basis for successful treatment and clinical compensation of mentioned diseases. The aim of my work was a proving of seven working hypotheses about compliance, attitude and sense to dietotherapy and questions determinated the influence to compliance assess- ment. Five hypotheses were confirmed and two ones refused. 128 respondents was included in the research group, included 40 patients with diabetes or obesity in the group with intensive intervention program, random selected group was consis- ted from 88 patients diabetes mellitus, hyperlipoproteinemias or obesity. The questionnaire was completed anonymously and computer program was used for statistical analysis and results demonstrated in tables and figures The positive changes of dietary regimen during the course of intensive intervention program were proved. Positive correlation between...

National Repository of Grey Literature : 62 records found   beginprevious36 - 45nextend  jump to record:
See also: similar author names
10 Dlouhý, Petr
Interested in being notified about new results for this query?
Subscribe to the RSS feed.