National Repository of Grey Literature 62 records found  beginprevious32 - 41nextend  jump to record: Search took 0.01 seconds. 
Omega-3 polyunsaturated fatty acids in human nutrition
Hrušovská, Veronika ; Dlouhý, Pavel (advisor) ; Rambousková, Jolana (referee)
This Bachelor thesis deals with the omega-3 polyunsaturated fatty acids used in nutrition. The thesis examines how well students of the Third Faculty of Medicine at the Charles University in Prague are informed about the omega-3 polyunsaturated fatty acids and to what extent they consume food rich in omega-3 polyunsaturated fatty acids. The theoretical part of the Bachelor thesis focuses on the basic fatty acids theory, the general characteristics of the omega-3 polyunsaturated fatty acids and the recommended intake of polyunsaturated fatty acids from foods. It addresses the effects of the omega-3 polyunsaturated fatty acids on the prevention and treatment of diseases, their effects on the lipid spectrum, the cardiovascular system, the immune system, the central nervous system and eyesight, diabetology, nutritional pharmacology and the skin. It deals with the significance of omega-3 polyunsaturated fatty acids intake by pregnant and lactating women, children, the elderly and vegans. It specifies the sources of omega-3 polyunsaturated fatty acids in nutrition. In the practical part of the Bachelor thesis, the author evaluates an interview survey involving 467 students in all years and from all branches of study at the Third Faculty of Medicine at the Charles University in Prague, who were enrolled in the...
Molecular mechanisms affected by n-3 polyunsaturated fatty acids
Hensler, Michal ; Flachs, Pavel (advisor) ; Rossmeislová, Lenka (referee) ; Dlouhý, Pavel (referee)
Adipose tissue and its hormones have an irreplaceable role in the physiology of mammals. The imbalance between energy intake and energy expenditure leads to the expansion of adipose tissue and changes in its secretion profile. With obesity are associated diseases including cardiovascular diseases, dyslipidemia, hypertension and insulin resistance, one of the major public health issues. Long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs) from marine origin, mainly eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids exert numerous beneficial effects, such as improvements of lipid metabolism and prevention of obesity and diabetes. Studies with obesity-prone model mice (C57BL/6) provide us important knowledge regarding their effect on mammalian tissues and to test potential therapeutic interventions. The thesis is based on five published studies (A-E). Three studies are focused on white adipose tissue. In these works we proved that adipose tissue is a flexible organ and LC n- 3 PUFAs are potent regulators of adipose tissue biology. Our results document that LC n- 3 PUFAs affect adipose tissue mass by a mechanism, which depends on counteraction of both, differentiation and proliferation of adipose cell (publication A). The anti-obesity effect of EPA and DHA could be magnified by mild calorie...

National Repository of Grey Literature : 62 records found   beginprevious32 - 41nextend  jump to record:
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10 Dlouhý, Petr
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