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The influence of high altitude on shooting efficiency of biathletes.
Boudíková, Adéla ; Dovalil, Josef (advisor) ; Pupiš, Martin (referee) ; Ondráček, Jan (referee)
The main purpose was describe the issue of shooting success rate at high altitude (1 500 - 3 000m a. s. l.). Shooting success rate of elite racers was evaluated using analysation of results from individual races at high altitude in the period 1990/1991 - 2013/2014. High altitude had no statistical effect (p<0,05) on shooting success rate of women and men biathletes in the comparision with lowland but it had more negative effect to women shooting success rate than men shooting success rate. Ten national level biathletes were tested in three tests in lowland, four tests at high altitude and five tests in lowland after the return from high altitude. The test included rest shooting in the prone and standing positions and load shooting in both positions which took part of three kilometers running. Twelve days training camp at high altitude did not improve shooting success rate, shooting velocity and running time in the determinated heart rate. Rest shooting and shooting in the prone position did not change statistically during the whole testing period. At high altitude critical days were registered in load shooting in standing position (6th day, p<0,05) and average running time (9th day, p<0,05). Rifle manipulation and shooting are automate motions which are not influenced by high altitude. Most...
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The influence of high altitude on shooting efficiency of biathletes.
Boudíková, Adéla ; Dovalil, Josef (advisor) ; Pupiš, Martin (referee) ; Ondráček, Jan (referee)
The main purpose was describe the issue of shooting success rate at high altitude (1 500 - 3 000m a. s. l.). Shooting success rate of elite racers was evaluated using analysation of results from individual races at high altitude in the period 1990/1991 - 2013/2014. High altitude had no statistical effect (p<0,05) on shooting success rate of women and men biathletes in the comparision with lowland but it had more negative effect to women shooting success rate than men shooting success rate. Ten national level biathletes were tested in three tests in lowland, four tests at high altitude and five tests in lowland after the return from high altitude. The test included rest shooting in the prone and standing positions and load shooting in both positions which took part of three kilometers running. Twelve days training camp at high altitude did not improve shooting success rate, shooting velocity and running time in the determinated heart rate. Rest shooting and shooting in the prone position did not change statistically during the whole testing period. At high altitude critical days were registered in load shooting in standing position (6th day, p<0,05) and average running time (9th day, p<0,05). Rifle manipulation and shooting are automate motions which are not influenced by high altitude. Most...
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The effects of dexrazoxane on ischemia-reperfusion injury in rat heart
Boudíková, Adéla ; Neckář, Jan (advisor) ; Hloušková, Patricie (referee)
Dexrazoxane (DEX) is clinically used to reduce cardiotoxic efects of anthracycline cytostatics. Its cardioprotective efect is caused by chelatation of free iron and defends myocard against dangerous hydroxyl radicals. This research finds out how dexrazoxane works in ischemic-reperfusion damages of rat's heart. Each rat was infused by DEX (50, 150, 450 mg/kg) or by control solution. Isolated perfused rat's hearts were exposed to local ischemia for 30 minutes than 10 minutes of reperfusion for studing ischemic arrhythmias followed by 15 minutes of local ischemia and 10 minutes of reperfusion to examine reperfusion arrhythmias. For evaluation of EKG (ventricular arrhythmias) was used software CAR and Lambeth convention. Global ischemias (15 min.) were induced in rat's hearts (DEX 150 mg/kg) and left ventricules were used for HPLC to determinate concentration of glutathion. In vivo experiments rats were infused by DEX 50, 150 mg/kg or control solution and were exposed for 20 minutes to local ischemia and for 3 hours to reperfusion. Infarct size was evaluated based on the cross section of heart (GIMP, Ellipse). Maximum total number of ischemic arrhytmias decreased by DEX 150 mg/kg (64% comparing to controls). Reperfusion score was reduced by DEX 150 to 48% and percents of ventricular fibrilation was...
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